Zearalenone toxicosis on reproduction as estrogen receptor selective modulator and alleviation of zearalenone biodegradative agent in pregnant sows

Table 4 Effects of MBA on serum hormones of first-parity gilts when exposed to ZEA^c

Items		Dietary treatment^d				Pooled SEM^e	Source of variation (P-value)
Items		CO	COA	MO	MOA	Pooled SEM^e	Main effect of ZEA	Main effect of MBA	ZEA × MBA
Serum hormones (60 d)	E2, pg/mL	115^b	117^b	162^a	111^b	14.58	0.1	0.07	< 0.01
	PROG, ng/mL	2.40	2.31	2.47	2.23	0.20	0.82	0.25	0.44
	T, pg/mL	67.2	67.2	62.4	69.3	4.29	0.69	0.34	0.31
	FSH, mIU/mL	5.00	5.07	5.73	4.99	0.42	0.20	0.22	0.10
	LH, mIU/mL	2.94^c	2.99^c	3.67^a	3.34^b	0.14	< 0.01	0.13	< 0.01
	PRL, mIU/mL	207	204	224	204	11.35	0.59	0.37	0.28
Serum hormones (114 d)	E2, pg/mL	31.03^a	38.41^a	76.63^b	59.35^c	4.27	< 0.01	0.11	< 0.01
	PROG, ng/mL	3.78^a	4.11^a	7.26^b	5.91^c	0.13	< 0.01	0.23	< 0.01
	T, pg/mL	68.43	67.44	64.76	66.44	11.90	0.97	0.84	0.90
	FSH, mIU/mL	5.83^a	6.22^a	10.82^b	8.81^c	0.47	< 0.01	0.43	< 0.01
	LH, mIU/mL	3.22^a	3.32^a	5.62^b	4.41^c	0.31	< 0.01	0.15	< 0.01
	PRL, mIU/mL	111.09^a	116.13^a	260.16^b	153.56^a	18.37	0.42	0.07	< 0.01

^a,b Mean values within a row without a common superscript differ significantly (P < 0.05)
^c Means represent eight replications per treatment (n = 8/group)
^d CO, a positive basal control diet contained 60.52% normal corn; COA, CO + 2 g MBA/kg diet; 3) MO, a negative basal control diet contained 60.52% moldy corn; MOA, MO + 2 g MBA/kg diet; ZEA Zearalenone, DON Deoxynivalenol, MBA Mycotoxin biodegradation agent, E2 Estradiol, PROG Progesterone, T Testosterone, LH Luteotrophic hormone, PRL Prolactin, FSH Follicle-stimulating hormone, MBA mycotoxin biodegradation agent
^e Pooled standard error of the means

ISSN: 2049-1891