Fig. 5

The abundances of agmatine, putrescine, spermidine and spermine in ovine conceptuses in which there was knockdown of translation of mRNAs for ODC1, ADC and their combination (ODC1: ADC). In vivo knockdown of ODC1 (n = 5), MAO-ODC1:ADC (a) (n = 2) and MAO-ODC1:MAO-ADC (b) (n = 4) increased agmatine (nmol/g) [a] in conceptus tissue. Knockdown of mRNAs for both ODC1 and ADC resulted in the MAO-ODC1: MAO-ADC (a) phenotype and tissues from those conceptuses had greater concentrations (nmol/g) of spermidine [b] and putrescine [c], but less spermine [d]. Means with different superscript letters are different (P < 0.05). Data are presented as mean and SEM