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Table 3 Effects of ATRA on growth performance and diarrhea of piglets challenged with TGEV

From: All-trans retinoic acid alleviates transmissible gastroenteritis virus-induced intestinal inflammation and barrier dysfunction in weaned piglets

Items

Control

TGEV

TGEV + ATRA5

TGEV + ATRA15

P-value

Initial BW, kg

7.63 ± 0.12

7.62 ± 0.12

7.64 ± 0.12

7.63 ± 0.13

0.993

d 14 BW, kg

11.34 ± 0.34

11.37 ± 0.32

12.01 ± 0.28

11.39 ± 0.28

0.367

d 19 BW, kg

13.40 ± 0.38ab

12.88 ± 0.39a

14.26 ± 0.36b

13.32 ± 0.32ab

0.077

d 14–19 (Post-challenge)

    

ADFI, g

669.20 ± 33.30b

563.00 ± 54.45a

711.33 ± 38.47b

647.15 ± 13.01ab

0.046

ADG, g

411.25 ± 18.46b

300.00 ± 47.96a

448.75 ± 24.53b

386.25 ± 19.72b

0.012

F/G

1.64 ± 0.09a

2.06 ± 0.20b

1.59 ± 0.03a

1.70 ± 0.07a

0.033

Diarrhea rate, %

0.00a

35.00b

5.00a

5.00a

< 0.001

  1. BW Body weight, ADFI Average daily feed intake, ADG Average daily gain, F/G Feed to gain ratio. Data are presented as mean ± SE. a,bValues in the same row with different superscripts letters are significantly different (P < 0.05)