Fig. 3
Significantly changed pathways (−log10(P) value > 1.5) in distal colon digesta oligosaccharide-based polymer groups and 50 mg/kg of carbadox on d 5 (A) or d 11 (C) post-inoculation. The x-axis represents the pathway impact values and the y-axis represents the −log10(P) values from the pathway enrichment analysis. Metabolite set enrichment analysis (B and D) shows the metabolic pathways were altered in 10 or 20 mg/kg oligosaccharide-based polymer active substance groups compared to carbadox on d 5 or d 11 post-inoculation, respectively. Both pathway analysis and metabolite set enrichment analysis were performed using identified metabolites with VIP > 1