Table 5 The mRNA levels of genes involved in different metabolic pathways in liver

Glucose transport

glut2a

0.75 ± 0.46

1.11 ± 0.50

1.16 ± 1.13

0.70 ± 0.63

NS

NS

NS

glut2b

0.79 ± 0.71^b

2.12 ± 1.67^a

1.13 ± 0.65^ab

0.82 ± 0.86^b

NS

NS

^**

Glycolysis

gcka

0.24 ± 0.35

2.59 ± 4.09

17.89 ± 8.13

12.07 ± 10.43

^***

NS

NS

gckb

0.27 ± 0.58^c

1.53 ± 1.34^bc

15.03 ± 7.15^a

5.58 ± 3.86^b

^***

^**

^***

pfkla

1.03 ± 1.05^b

2.71 ± 2.30^a

1.13 ± 0.62^b

0.73 ± 0.72^b

^*

NS

^*

pfklb

0.97 ± 0.81^b

2.43 ± 2.15^a

1.33 ± 0.75^ab

0.84 ± 0.85^b

NS

NS

^*

pk

0.93 ± 0.81^b

2.23 ± 1.56^a

1.05 ± 0.74^b

0.67 ± 0.55^b

^*

NS

^**

Gluconeogenesis

pck1

1.85 ± 1.62

2.26 ± 2.42

0.98 ± 1.26

0.94 ± 1.38

^*

NS

NS

pck2

1.26 ± 1.31

2.09 ± 2.22

1.44 ± 0.80

0.96 ± 1.32

NS

NS

NS

fbp1a

0.59 ± 0.52

1.72 ± 1.44

0.76 ± 0.81

1.13 ± 1.48

NS

^*

NS

fbp1b1

1.11 ± 1.21^ab

2.32 ± 1.68^a

0.76 ± 0.45^b

0.59 ± 0.68^b

^**

NS

^*

fbp1b2

1.35 ± 1.71

1.97 ± 1.47

1.01 ± 0.76

0.46 ± 0.38

^*

NS

NS

g6pca

1.07 ± 1.18

2.45 ± 2.01

1.20 ± 0.83

1.01 ± 1.10

NS

NS

NS

g6pcb1b

1.09 ± 0.70

1.31 ± 1.28

1.28 ± 1.00

1.32 ± 1.25

NS

NS

NS

g6pcb2a

0.59 ± 0.65^b

2.75 ± 2.58^a

2.55 ± 2.08^ab

0.88 ± 1.23^ab

NS

NS

^**

Lipogenesis

srebf1

0.61 ± 0.77^b

2.77 ± 2.10^a

1.90 ± 1.34^ab

0.89 ± 1.27^b

NS

NS

^***

g6pdb

0.67 ± 0.66

2.11 ± 1.75

1.07 ± 0.75

1.02 ± 1.49

NS

NS

NS

aclyb

0.76 ± 0.66^b

1.60 ± 1.03^ab

2.16 ± 1.37^a

0.80 ± 1.01^b

NS

NS

^**

aclyc

0.85 ± 0.81^b

2.76 ± 2.33^a

2.18 ± 1.29^ab

0.75 ± 0.52^ab

NS

NS

^***

aca-aa

1.20 ± 1.72

2.67 ± 2.74

3.28 ± 2.89

2.65 ± 3.29

NS

NS

NS

aca-ba

1.59 ± 1.37

2.84 ± 2.27

0.84 ± 0.53

0.80 ± 0.75

^**

NS

NS

fasna

0.81 ± 0.48

1.06 ± 0.56

1.43 ± 1.17

1.37 ± 1.70

NS

NS

NS

fasnb

1.24 ± 1.00

1.40 ± 0.503

1.25 ± 0.81

1.22 ± 1.06

NS

NS

NS

Cholesterol biosynthesis

srepb2a

1.05 ± 1.15

1.79 ± 1.20

1.19 ± 0.59

1.06 ± 1.15

NS

NS

NS

srepb2b

1.04 ± 0.90

1.70 ± 1.18

0.88 ± 0.35

0.70 ± 0.63

^*

NS

NS

hmgcra

0.94 ± 0.74

1.19 ± 0.80

1.11 ± 0.85

1.01 ± 1.12

NS

NS

NS

hmgcrb

1.58 ± 1.21

1.26 ± 0.84

0.92 ± 0.59

0.70 ± 0.63

^*

NS

NS

dhcr7a

1.34 ± 0.99

1.43 ± 1.09

0.77 ± 0.59

0.76 ± 0.78

^*

NS

NS

dhcr7b

0.99 ± 0.41

1.16 ± 0.85

0.49 ± 0.22

0.85 ± 0.78

NS

NS

NS