Fig. 8
From: Regulation of serotonin production by specific microbes from piglet gut
The effect of acetate on its receptors in RIN-14B cells. A The effect of acetate on its receptors mRNA expression. The effect of AR420626 on TPH1 (B), IDO1 (C) and SERT (D) mRNA expression. All values are mean ± SEM. n = 6 per group. The Student's t-test was performed between two groups while asterisks mean statistically significant difference: *P < 0.05, ****P < 0.0001. ACSS2: Acetyl-CoA synthetase 2; HDAC: Histone deacetylation. FFAR2: Free fatty acid receptor 2; FFAR3: Free fatty acid receptor 3; Olfr78: Olfactory receptor 78; Olfr558: Olfactory receptor 558; TPH1: Tryptophan hydroxylase 1; IDO1: Indoleamine 2,3-dioxygenase 1; SERT: Serotonin reuptake transporter