Fig. 6
From: Regulation of serotonin production by specific microbes from piglet gut
The bacterial metabolites promote 5-HT synthesis in IPEC-J2 and RIN-14B cells. The effect of bacterial metabolites on TPH1 (A), IDO1 (B), and SERT (C) mRNA expression in IPEC-J2 cells. The effect of acetate on TPH1 (D) and IDO1 (E) mRNA expression in RIN-14B cells. All values are mean ± SEM. n = 6 per group. The Student's t-test was performed between two groups while asterisks mean statistically significant difference: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. TPH1: Tryptophan hydroxylase 1; IDO1: Indoleamine 2,3-dioxygenase 1; SERT: Serotonin reuptake transporter