Fig. 3

Pathway analysis of the differentially expressed genes in milk somatic cells. a ClueGO functionally grouped network of up and downregulated genes within the healthy and Prototheca’s infected cows. b ClueGO functionally grouped network of up and downregulated genes within the healthy and S. agalactiae’s infected cows. Terms are represented as nodes linked according to a kappa score ≥ 0.4. The node size means the term enrichment significance. Functionally related groups partially overlap. c Heatmap built on the pathway deregulation scores (PDSs) of the whole transcriptomic data of healthy, Prototheca’s, and S. agalactiae’s infected animals. Each row corresponds to a pathway, and each column to a sample. Blue corresponds to “no deregulation”, and yellow to high deregulation