Fig. 8From: CLOCK inhibits the proliferation of porcine ovarian granulosa cells by targeting ASB9Schematic diagram of CLOCK regulation on porcine GC proliferation. CLOCK inhibits cell proliferation by promoting ASB9 expression in porcine ovarian GCs. Specifically, CLOCK and BMAL1 complex binds to the E-box element of ASB9 promoter to increase the level of ASB9. Then, ASB9 inhibits GC proliferation by regulating cell cycleBack to article page