Cecal microbiota transplantation: unique influence of cecal microbiota from divergently selected inbred donor lines on cecal microbial profile, serotonergic activity, and aggressive behavior of recipient chickens

Table 4 Effects of cecal microbiota transplantation on relative mRNA expression of genes involved in the serotonergic pathway in the hypothalamus of recipient chickens at week 5 and week 16

Treatment	MAOA	TPH2	5-HTT	Htr1a	Htr1b
Week 5
6₃-CMT	1.51	0.33	1.12	1.47	1.19
7₂-CMT	1.56	0.45	0.72	1.44	1.45
Control	1.45	0.40	0.92	1.50	1.36
SEM	0.11	0.05	0.17	0.11	0.13
P-value	0.80	0.31	0.26	0.93	0.37
Week 16
6₃-CMT	2.52^a	0.83	1.63	0.86	2.35
7₂-CMT	1.80^b	0.84	1.54	0.77	2.32
Control	1.90^ab	1.00	2.04	0.81	2.12
SEM	0.05	0.12	0.21	0.07	0.09
P-value	0.02	0.45	0.23	0.67	0.18

^a,b Means with different superscript indicate significant difference (P ≤ 0.05). Values are least square means ± SEM, n = 7. 5-HTT erotonin transporter, 6₃-CMT Received cecal content solution from 6₃ donors, 7₂-CMT Received cecal content solution from 7₂ donors, CTRL Received saline, control. Htr1a 5-HT 1a receptor, Htr1b 5-HT 1b receptor, TPH2 Tryptophan hydroxylase 2, MAOA Monoamine oxidase A

ISSN: 2049-1891