Fig. 4
From: Mori fructus aqueous extracts attenuates liver injury by inhibiting ferroptosis via the Nrf2 pathway
MFAEs improve hepatic function and structure in CCl4-induced chronic liver injury mice. A Outline of experimental procedures to examine the role of MFAEs in the mouse 10% CCl4-induced chronic liver model. B Blood glucose and liver indices. C Representative liver image, H&E and eosinophil staining images of liver sections in indicated mice. Bar, 100 μm (100× and 200×), 50 μm (400×). n = 5 per group. LFS: Long fiber spacing, HL: Hepatic lobule, HS: Hepatic sinusoid, HC: Hepatic cord. Yellow arrow: hepatocyte edema, blue arrow: inflammatory cell infiltration, yellow triangle: eosinophilic corpuscle. D Pathological scores. E Serum ALT, AST, γ-GT and LDH activity, serum TP, TBIL and TBA contents in the indicated mice. *Indicates a significant difference compared with the control group (*P < 0.05, **P < 0.01). #Indicates a significant difference compared with the 10% CCl4 group (#P < 0.05, ##P < 0.01)