Fig. 1
From: Mori fructus aqueous extracts attenuates liver injury by inhibiting ferroptosis via the Nrf2 pathway
MFAEs restored hepatic function and structure in CCl4-induced acute liver injury mice. A Outline of experimental procedures for CCl4-induced acute liver mouse model. B Blood glucose. n = 8 samples per group. C Representative liver image, H&E and eosinophil staining images of liver sections as indicated. Bar, 100 μm (100× and 200×), 50 μm (400×). n = 5 per group. CN: Coagulative necrosis, HL: Hepatic lobule, HS: Hepatic sinusoid, HC: Hepatic cord. Yellow arrow: hepatocyte edema, Blue arrow: inflammatory cell infiltration, yellow triangle: eosinophilic corpuscle. Blue triangle: lipid degeneration. D Pathological scores. E Serum ALT and AST activity, serum and liver tissue TBIL and TBA contents in the indicated mice. Values are expressed as mean ± SD. One-way ANOVA with Tukey’s analysis was used. *Indicates a significant difference compared with the control group (*P < 0.05, **P < 0.01). #Indicates a significant difference compared with the 0.3% CCl4 group (#P < 0.05, ##P < 0.01)