Fig. 3
From: Ferroptosis is involved in deoxynivalenol-induced intestinal damage in pigs
Effects of DON on the expression of ferroptosis-related genes in duodenum. The relative mRNA abundance of ferroptosis-related genes in duodenum (A). Values are expressed as means ± SD, n = 7. A representative image (B) and the relative density (C) of protein bands of ferroptosis-related proteins in duodenum. Values are expressed as means ± SD, n = 3. Labeled means without a common letter differ, P < 0.05. Control, base diet; 1.0 DON, basal diet supplemented with 1.0 mg/kg DON; 3.0 DON, basal diet supplemented with 3.0 mg/kg DON. ACSL4, acyl-CoA synthetase long chain family member 4; ALOX5, arachidonate 5-lipoxygenase; ALOX12, arachidonate 12-lipoxygenase, 12S type; ALOX15, arachidonate 15-lipoxygenase; CISD1, CDGSH iron sulfur domain 1; DMT1, divalent metal transporter 1; FTL, ferritin light chain; FPN, ferroportin; FTH1, ferritin heavy chain 1; FSP1, ferroptosis suppressor protein 1; GPX4, glutathione peroxidase 4; HSPB1, heat shock protein family B (small) member 1; SLC7A11, solute carrier family 7 member 11; STEAP3, six-transmembrane epithelial antigen of prostate 3; TFR1, transferrin receptor