Fig. 6

Heat maps of the Spearman rank correlation coefficient and significant tests between the differential bacteria and tryptophan metabolites (A). Pairwise comparisons if metabolites are demonstrated with a color gradient denoting Spearman’s correlation coefficient. Trp, ST, IAA, IPA, HIAA, and Tpm are related to inflammatory cytokines, jejunum morphology indices by partial spearman tests. Edge width corresponds to the Partial Spearman’s r statistic for the corresponding distance correlations and edge color denotes the statistical significance (B). Data are presented as the mean ± SE, (n = 6). ^*P < 0.05; ^**P < 0.01; ^***P < 0.001