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Table 3 Effect of supplemental C. butyricum on the content of TC and its metabolite in the serum and liver of IUGR suckling piglets

From: Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling piglets

Items1

NBW-CON2

IUGR-CON

IUGR-CB

P-values

1

2

3

Serum

      

  TC, mmol/L

6.83 ± 0.57

5.28 ± 0.72

6.38 ± 0.57

0.208

0.865

0.443

  HDL-C, mmol/L

3.28 ± 0.17

2.47 ± 0.19*

3.54 ± 0.23#

0.022

0.636

0.003

  LDL-C, mmol/L

3.55 ± 0.31

2.80 ± 0.29

2.83 ± 0.23

0.165

0.186

0.997

Liver

      

  TC, mmol/gprot

56.27 ± 3.62

72.54 ± 2.54*

58.11 ± 3.12#

0.004

0.910

0.010

  TBA, µmol/gprot

7.12 ± 0.48

5.62 ± 0.33*

7.21 ± 0.40#

0.041

0.988

0.030

  1. All data are presented as mean ± SE (n = 8). Significant difference is depicted as *P < 0.05 when compared with NBW-CON, #P < 0.05 when compared with IUGR-CON group. Contrast: (1) NBW-CON versus IUGR-CON; (2) NBW-CON versus IUGR-CB; (3) IUGR-CON versus IUGR-CB
  2. 1TC, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; TBA, total bile acid
  3. 2NBW-CON, piglets with normal birth weight; IUGR-CON, piglets with intrauterine growth restriction; IUGR-CB, piglets with intrauterine growth restriction supplemented with Clostridium butyricum