Fig. 3From: Supplemental Clostridium butyricum modulates lipid metabolism by reshaping the gut microbiota composition and bile acid profile in IUGR suckling pigletsEffect of supplemental C. butyricum on cholesterol and BA metabolism of IUGR suckling piglets. A The mRNA abundance of genes related to cholesterol synthesis and efflux. B The mRNA abundance of genes related to BA synthesis and excretion. C The protein levels of LXRα, CYP7A1 and CYP27A1. The column and its bar represented the means value and SE (n = 8), respectively. Significant difference is depicted as *P < 0.05 when compared with NBW-CON, #P < 0.05 when compared with IUGR-CON group. SREBF2, sterol-regulatory element binding factor 2; LXRα, liver X receptor α; ABCA1, ATP-binding cassette transporter A1; ABCG1, ATP-binding cassette transporter G1; ABCG5, ATP-binding cassette transporter G5; ABCG8, ATP-binding cassette transporter G8; SCARB1, scavenger receptor B class I; CYP7A1, cholesterol 7 α-hydroxylase; CYP27A1, cholesterol 27 α-hydroxylase; CYP7B1, Cytochrome P450 Family 7 Subfamily B Member 1; CYP8B1, Cytochrome P450 Family 8 Subfamily B Member 1; BSEP, bile salt export pump; MRP2, multidrug resistance associated protein 2; NBW-CON, piglets with normal birth weight; IUGR-CON, piglets with intrauterine growth restriction; IUGR-CB, piglets with intrauterine growth restriction supplemented with Clostridium butyricumBack to article page