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Fig. 9 | Journal of Animal Science and Biotechnology

Fig. 9

From: Isorhamnetin protects porcine oocytes from zearalenone-induced reproductive toxicity through the PI3K/Akt signaling pathway

Fig. 9

Isorhamnetin inhibited ZEA-caused apoptosis through the PI3K/Akt signaling pathway.Oocytes were co-cultured in ZEA (5 μmol/L), ISO (10 μmol/L) and LY294002 (20 μmol/L) for 44 h. A Representative pictures of apoptosis in Control, ZEA, ZEA + ISO and ZEA + ISO + LY294002. B The percentage of positive Annexin-V. C Western blot of Bcl-2 and Bax protein in Control, ZEA, ZEA + ISO and ZEA + ISO + LY294002. D–F The ratios of Bcl-2 to GAPDH, Bax to GAPDH and Bax to Bcl-2 expression were normalized, respectively. Various letters (P < 0.05) designate significant differences. Data are presented by average ± SEM

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891