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Fig. 5 | Journal of Animal Science and Biotechnology

Fig. 5

From: Sodium butyrate alleviates deoxynivalenol-induced hepatic cholesterol metabolic dysfunction via RORγ-mediated histone acetylation modification in weaning piglets

Fig. 5

Histone acetylated marks H3K27ac and H3K9ac contribute to NaBu-modulated key cholesterol biosynthetic genes. A Visualisation of ChIP-seq signal of histone H3K27ac at indicated cholesterol homeostasis genes HMGCR, SQLE, DHCR24, HSD17B7, and LDLR. B, C ChIP-qPCR analysis of the relative enrichment of histone H3K27ac (B) and H3K9ac (C) at the HMGCR, SQLE, and DHCR24 loci. Data are presented as the means ± SEM of at least three independent experiments. *P < 0.05, **P < 0.01. *Compared with the Vehicle group; #compared with the DON group. One-way ANOVA was used

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891