Table 2 Effect of intrauterine growth retardation (IUGR) on bile acid derivatives in colonic contents of pigs at piglet stages

Apocholic acid

NBW

0.04 ± 0.03

0.09 ± 0.03

0.17 ± 0.26

IUGR

0.42 ± 0.29

0.07 ± 0.05

0.12 ± 0.09

Cholic acid

NBW

0.37 ± 0.18

0.43 ± 0.11

0.68 ± 0.23

IUGR

0.58 ± 0.35^b

0.30 ± 0.05^b

1.28 ± 0.38^a

Dehydrolithocholic acid

NBW

1.91 ± 0.82^b

12.65 ± 3.91^a

6.97 ± 2.72^ab

IUGR

4.28 ± 1.84

8.14 ± 1.86

10.73 ± 6.27

Glycochenodeoxycholic acid

NBW

0.63 ± 0.09

0.31 ± 0.11

0.27 ± 0.09

IUGR

0.76 ± 0.21

0.23 ± 0.08

0.26 ± 0.09

Glycohyodeoxycholic acid

NBW

0.17 ± 0.03

0.63 ± 0.09

1.39 ± 0.45

IUGR

0.19 ± 0.08

0.45 ± 0.08

1.60 ± 0.57

Hyodeoxycholic acid

NBW

37.76 ± 10.55^b

247.54 ± 94.80^ab

779.47 ± 270.20^a

IUGR

28.90 ± 10.42^b

216.70 ± 91.79^b

906.24 ± 267.16^a

Hyocholic acid

NBW

159.60 ± 87.02

116.88 ± 8.78

50.83 ± 40.58

IUGR

184.73 ± 80.98

119.27 ± 61.12

315.06 ± 128.99

Isoallolithocholic acid

NBW

14.09 ± 5.78^b

27.35 ± 4.93^ab

30.02 ± 9.56^a

IUGR

11.79 ± 2.7

18.30 ± 9.53

28.52 ± 11.11

Isolithocholic acid

NBW

17.45 ± 7.89^b

49.41 ± 15.69^ab

76.39 ± 29.96^a

IUGR

11.45 ± 4.74

29.45 ± 8.32

84.17 ± 42.17

Lithocholic acid

NBW

54.92 ± 17.72^b

139.63 ± 35.88^ab

245.69 ± 72.42^a

IUGR

52.82 ± 19.30^b

106.29 ± 31.44^ab

254.22 ± 79.72^a

α-muricholic acid

NBW

1.56 ± 0.41

13.6 ± 9.93

34.06 ± 24.64

IUGR

0.94 ± 0.33^b

15.62 ± 10.26^ab

39.78 ± 22.77^a

β-muricholic acid

NBW

0.63 ± 0.11^b

3.69 ± 1.59^b

10.09 ± 4.96^a

IUGR

0.30 ± 0.03^b

2.67 ± 1.14^b

10.55 ± 4.39^a

Ursocholic acid

NBW

0.19 ± 0.06^b

0.37 ± 0.16^b

0.92 ± 0.23^a

IUGR

0.21 ± 0.11^b

0.22 ± 0.07^b

1.30 ± 0.49^a

Ursodeoxycholic acid

NBW

39.12 ± 10.44^b

254.21 ± 97.32^b

790.07 ± 275.45^a

IUGR

29.29 ± 10.42^b

222.67 ± 93.55^b

944.53 ± 279.74^a