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Table 1 The base change sites and phenotypes of alleles of ALV receptors

From: Advances on genetic and genomic studies of ALV resistance

Subgroup

Receptor

Alleles

Mutation mechanism

Base changes

Phenotype

ALV-A/K

Tva

Tva

-

-

Sensitive

Tvar

Base mutation

C/G 168 mRNA

Resistant

Tvar2

Exon 1 insert 4 bp

284CTGC287

Resistant

Tvar3

Intron 1 miss 10 bp

507ACCCCGCCCC516

Reduce susceptibility

Tvar4

Intron 1 miss 5 bp

507ACCCC511

Reduce susceptibility

Tvar5

Intron 1 miss 10 bp

502CGCTCACCCC511

Reduce susceptibility

Tvar6

Intron 1 miss 15 bp

502CGCTCACCCCGCCCC516

Reduce susceptibility

ALV-B/D/E

Tvb

Tvbs1

-

-

Sensitive to subgroups B/D/E

Tvbs3

Base mutation

T/A 184 mRNA

Sensitive to subgroups B/D

Tvbr

Base mutation

C/T 172 mRNA

Resistant

ALV-C

Tvc

Tvc

-

-

Sensitive

Tvcr

Base mutation

C/A165 mRNA

Resistant

ALV-J

NHE1

NHE1

-

-

Sensitive

NHE1

Base mutation

W38

Resistant

  1. “-” means no change. The superscript numbers indicate gene loci