Fig. 4

RS is associated with alleviative inflammatory reaction promotes. a The transcription of tumour necrosis factor alpha (TNF-α), interleukin (IL)-1β and IL-10 in ileum. b The levels of TNF-α, IL-1β, IL-17, and IL-10 in serum from different groups. c The mRNA expression of inflammatory cytokines in bone marrow including TNF-α, IL-1β, IL-17, IL-10, nuclear factor-κB (NF-κB), and mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Malt1). d The correlations between the relative abundance of intestinal bacterial genera with the mRNA level of IL-10, IL-1β, NF-κB, Malt, and TNF-α in bone marrow. Data are expressed as mean and standard deviation.^a−cMean values with different letters are significantly different by one-way analysis of variance followed by Tukey’s post hoc test (P < 0.05). * and ** denoted significant correlation at P < 0.05 and P < 0.01, respectively