Microencapsulated essential oils combined with organic acids improves immune antioxidant capacity and intestinal barrier function as well as modulates the hindgut microbial community in piglets

Table 4 Serum immune function and antioxidant status of piglets as affected by dietary AGP and MOA supplementation ¹

Item	Ctrl	AGP	MOA	SEM	P-value
Day 11
IgA, μg/mL	19.58	19.51	19.74	0.72	0.97
IgG, mg/mL	9.16	9.07	9.23	0.41	0.96
IgM, μg/mL	7.06	7.10	8.05	0.34	0.18
IL-1β, ng/L	92.68	94.21	92.86	1.71	0.80
IL-10, ng/L	17.71^b	17.83^b	21.69^a	0.61	0.02
IFN-γ, pg/mL	196.74	197.34	195.90	6.75	0.98
TNF-α, ng/L	56.78	58.79	56.88	1.02	0.38
GSH-Px, μmol/L	8.09^b	12.24^ab	15.50^a	0.83	0.01
SOD, U/mL	109.56	124.03	129.65	4.36	0.07
T-AOC, U/mL	10.41^a	7.83^b	11.16^a	0.45	0.01
MDA, nmol/mL	1.48	1.46	1.30	0.10	0.46
Day 21
IgA, μg/mL	18.04	19.26	18.64	0.54	0.37
IgG, ng/L	8.57	8.22	8.60	0.14	0.22
IgM, μg/mL	7.17	7.91	8.07	0.21	0.07
IL-1β, ng/L	102.81	101.70	103.90	2.19	0.79
IL-10, ng/L	17.19	18.62	19.57	0.47	0.06
IFN-γ, pg/mL	194.25	201.16	200.61	6.34	0.71
TNF-α, ng/L	50.63	50.88	48.65	1.05	0.36
GSH-Px, μmol/L	13.05	15.46	17.00	1.05	0.13
SOD, U/mL	125.66^b	143.28^b	169.51^a	5.08	0.01
T-AOC, U/mL	10.46	10.62	10.93	0.72	0.90
MDA, nmol/mL	1.37	1.53	1.27	0.11	0.32

IgA, IgG, IgM, immunoglobulin A, G, M; IL-1β, IL-10, interleukin-1β, 10; IFN-γ, gamma-interferon; TNF-α, tumor necrosis factor-α; T-AOC, total antioxidant capacity; MDA, malondialdehyde; GSH-Px, glutathione peroxidase; SOD, serum superoxide dismutase
^a,bMeans in the same row with different superscripts are significantly different (P < 0.05)
¹Control (Ctrl): a corn soybean meal-based diet. AGP: Ctrl + 75 mg/kg chlortetracycline. MOA: Ctrl + 1500 mg/kg MOA. n = 4

ISSN: 2049-1891