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Table 6 Differentially abundant serum metabolites between DF 1.0 and DF 1.75 gilts identified in positive and negative ionisation modes1,2

From: Microbial and metabolomic mechanisms mediating the effects of dietary inulin and cellulose supplementation on porcine oocyte and uterine development

Name Fold change P-value Name Fold change P-value
Positive ionisation    Negative ionisation   
(2S)-1-Hydroxy-3-(pentadecanoyloxy)-
2-propanyl (15Z)-15-tetracosenoate
18.966 0.047 Sinapyl alcohol 27.041 0.044
3-(2,4-Cyclopentadien-1-ylidene)-
5alpha-androstan-17beta-ol
5.594 0.003 Cuauhtemone 13.210 <  0.001
Oxandrolone 5.563 0.013 Cholic acid glucuronide 8.250 0.025
2,6-Di-tert-butyl-1,4-benzoquinone 5.028 0.005 GLIMEPIRIDE, CIS- 5.853 <  0.001
19-Nortestosterone 4.993 0.007 Olivoretin D 5.543 0.013
3-Beta-fluoro-5-beta-pregnan-20-one 4.670 0.002 Deoxycholic acid 4.117 0.001
p-Cymene 4.148 0.008 Avasimibe 3.204 0.026
Geroquinol 3.979 0.006 Taurochenodeoxycholic acid 3.100 0.044
Hypaphorine 3.902 <  0.001 p-Dimethylinamyl benzoate 3.077 <  0.001
Jasmonal 3.766 0.007 Chaksine 3.026 0.003
Ibuprofen 3.680 0.002 Tenivastatin 2.962 0.009
3-Beta,17-beta-diacetoxy-5α-androstane 3.057 0.007 Mupirocin 2.918 0.047
Oleandomycin 2′-O-phosphate 2.998 0.041 Ubiquinone Q4 2.219 0.025
Ionene 2.869 0.049 Sunitinib 2.185 0.011
Diaziquone 2.858 <  0.001 (3alpha)-3-Hydroxycholan-24-oic acid 2.054 0.042
1-Piperideine 2.857 0.004 Ifetroban 2.038 0.010
Myxalamid A 2.801 0.045 Maleimide 1.918 0.012
Genistein 2.584 0.011 5-HT 1.855 0.003
7-Ketodeoxycholic acid 2.434 0.023 Uldazepam 1.814 0.018
1-O-[4-(1H-indol-3-yl)butanoyl]
-beta-D-glucopyranose
2.335 0.001 Indole-3-carboxilic acid-O-sulphate 1.690 0.019
Linagliptin 2.278 0.017 6α-Prostaglandin I1 0.566 0.011
(KDO)2-lipid IVA 2.096 0.045 3-Hydroxydecanoic acid 0.548 0.021
4-Aminobenzoic acid 2.089 0.043 14,18-Dihydroxy-12-oxo-9,13,15-octadecatrienoic acid 0.542 < 0.001
Spermidine 1.964 0.026 Cromoglicic acid 0.531 < 0.001
Hexoprenaline 1.902 0.005 Nemonapride (JAN) 0.526 0.044
Manumycin 1.899 0.041 Epithienamycin F 0.519 0.010
N-Lactoyl ethanolamine phosphate 1.888 0.002 10-Undecenoic acid 0.508 0.010
Perphenazine enantate 1.862 0.003 Prunin 0.502 0.010
5-HIAA 1.856 0.002 Leucodelphinidin 0.497 0.001
TU4153400 1.831 0.036 MFCD00065806 0.496 0.015
1-Octadecanoyl-2-[(15Z)-
tetracosenoyl]-sn-glycero-3-phosphocholine
1.855 0.044 4,6,8-Trihydroxy-7-methoxy-3-methyl-3,4-dihydroisochromen-1-one 0.494 0.029
Bikhaconitine 1.850 0.007 ARAMITE 0.485 0.024
Cediranib 1.797 0.002 Uridine 0.480 0.013
Callystatin A 1.782 0.017 N-Palmitoyl-L-phenylalanine 0.463 0.014
Decoside 1.690 0.005 Cidofovir anhydrous 0.460 0.004
5-methyltetrahydropteroyltri-
L-Glutamic acid
1.677 0.012 3-Indoxyl sulphate 0.448 0.002
2-(2-Carboxyethyl)-4-methyl-
5-Pentyl-3-furoic acid
1.640 0.012 Butoctamide semisuccinate 0.447 0.009
Trans-Anethole 1.637 0.021 Kukoamine A 0.443 0.001
Saccharocin 1.541 0.002 Pyrophosphoric Acid 0.433 0.033
5-Phospho-beta-D-ribosylamine 1.540 0.009 4-Phenolsulfonic acid 0.429 0.046
Dehydrocholic acid 1.50 0.013 Geranyl phosphate 0.412 0.043
Tritoqualine 0.634 0.008 Caftaric acid 0.412 0.008
Benzoyl cyanide 0.628 < 0.001 Disulfaton 0.396 0.023
Ocaperidone 0.622 0.012 4-(1,2-Dihydroxy-2-propanyl)-1-methyl-1,2-cyclohexanediol 0.388 0.021
Monomethyl phosphate 0.621 0.002 Hydrogen bromide 0.363 < 0.001
MFCD00056202 0.619 0.019 (2-Hydroxy-2-oxido-1,3,2-dioxaphospholan-4-yl) methyl palmitate 0.316 0.004
Minosaminomycin 0.589 0.037 Chloralodol 0.228 < 0.001
Trametinib 0.557 0.003 Caprylic acid 0.199 0.024
Premithramycin A3’ 0.550 0.004 1,3-Nonanediol acetate 0.187 0.039
Alpha,alpha’-trehalose 6-mycolate 0.546 0.005 Retosiban 0.170 < 0.001
1-stearoyl-2-arachidonoyl-
sn-glycero-3-phosphoserine
0.521 0.033 3-Hydroxytridecanoic acid 0.155 0.009
Phytosphingosine 0.521 0.016 Difluprednate 0.126 < 0.001
Depe 0.484 0.006 Leukotriene B4 0.075 < 0.001
Azithromycin 0.462 0.001 Pentachlorophenol 0.071 < 0.001
1-Stearoyl-2-docosahexanoyl-
sn-glycero-3-phosphocholine
0.461 0.037 3,4,15-Triacetoxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate 0.055 < 0.001
Benzyl succinate 0.458 0.003 Nobiletin 0.029 < 0.001
Ascidiacyclamide 0.457 0.005    
1,2-Dioleoyl-sn-glycero-3-phospho-
N,N-dimethylethanolamine
0.436 0.011    
12-Deoxyoligomycin A 0.433 0.011    
Terminalin 0.420 0.036    
Digitoxin 0.415 0.028    
Uroporphyrinogen IV 0.362 0.009    
Vilazodone 0.361 0.001    
N,N-Bis(2-hydroxyethyl)
dodecanamide
0.334 0.002    
1-Eicosyl-2-docosanoyl-sn-glycero-3-
phosphocholine
0.307 0.042    
Emblicanin A 0.275 0.007    
Phytolaccoside B 0.221 0.025    
  1. Serum samples collected on 19 d of the 2nd oestrous cycle. Metabolites with VIP > 1, P-value < 0.05, fold change ≥ 1.5 or fold change ≤ 0.65 were considered differential metabolites