Table 5 Relative abundance of the top 53 microbiota at the genus level¹,%

6.33 ± 0.37

6.70 ± 0.80

6.34 ± 0.65

7.10 ± 1.04

0.440

0.895

2.21 ± 0.16^c

2.60 ± 0.46^bc

4.98 ± 1.10^a

3.81 ± 0.32^ab

< 0.001

0.660

3.46 ± 0.54^ab

2.52 ± 0.30^b

4.77 ± 0.73^a

5.14 ± 0.92^a

0.025

0.034

4.23 ± 0.63

2.98 ± 0.57

4.94 ± 0.58

4.78 ± 0.79

0.368

0.119

4.33 ± 0.31^bc

3.95 ± 0.33^c

5.61 ± 0.34^ab

5.80 ± 0.40^a

0.001

0.045

3.83 ± 0.28^b

5.90 ± 0.56^a

3.50 ± 0.50^b

2.87 ± 0.29^b

0.027

< 0.001

2.05 ± 0.32

2.66 ± 0.79

1.34 ± 0.38

1.89 ± 0.28

0.413

0.726

2.61 ± 0.27

3.16 ± 0.37

2.17 ± 0.23

2.15 ± 0.21

0.069

0.079

2.46 ± 0.29^a

2.68 ± 0.16^a

1.85 ± 0.10^b

1.49 ± 0.11^b

< 0.001

0.001

2.32 ± 0.26

2.24 ± 0.26

2.27 ± 0.24

2.15 ± 0.18

0.620

0.895

1.98 ± 0.30^a

1.61 ± 0.17^ab

1.00 ± 0.12^c

1.11 ± 0.15^bc

< 0.001

0.845

1.88 ± 0.36

1.85 ± 0.69

0.87 ± 0.17

1.30 ± 0.50

0.089

0.838

2.42 ± 0.21

2.36 ± 0.21

2.30 ± 0.12

2.46 ± 0.24

0.989

0.571

2.06 ± 0.08^a

2.42 ± 0.22^a

1.58 ± 0.15^b

1.51 ± 0.08^b

0.001

0.001

1.54 ± 0.37

1.24 ± 0.22

1.27 ± 0.34

1.67 ± 0.38

0.934

0.212

1.43 ± 0.08^ab

1.50 ± 0.12^a

1.18 ± 0.10^b

1.16 ± 0.06^b

0.008

0.169

1.42 ± 0.08

1.32 ± 0.09

1.42 ± 0.14

1.41 ± 0.07

0.944

0.532

1.36 ± 0.14

1.31 ± 0.12

1.12 ± 0.12

1.18 ± 0.11

0.149

0.922

1.34 ± 0.13

1.28 ± 0.24

1.69 ± 0.14

1.92 ± 0.20

0.027

0.188

1.28 ± 0.09^bc

1.25 ± 0.20^c

1.97 ± 0.15^a

1.88 ± 0.17^ab

0.002

0.382

1.12 ± 0.11

1.13 ± 0.08

0.94 ± 0.08

0.85 ± 0.06

0.011

0.191

1.00 ± 0.09

0.77 ± 0.10

0.79 ± 0.14

0.96 ± 0.14

0.680

0.095

0.98 ± 0.08

1.03 ± 0.16

0.82 ± 0.09

0.88 ± 0.10

0.271

0.710

0.87 ± 0.09^a

1.10 ± 0.16^a

0.60 ± 0.06^b

0.57 ± 0.03^b

< 0.001

0.010

0.81 ± 0.08

0.66 ± 0.10

1.01 ± 0.12

1.04 ± 0.09

0.055

0.080

0.71 ± 0.04

0.67 ± 0.08

0.76 ± 0.03

0.81 ± 0.05

0.147

0.256

0.66 ± 0.13

0.36 ± 0.06

0.78 ± 0.15

0.89 ± 0.21

0.154

0.010

0.60 ± 0.06

0.68 ± 0.06

0.50 ± 0.04

0.52 ± 0.04

0.093

0.168

0.56 ± 0.22^a

0.37 ± 0.09^ab

0.15 ± 0.02^c

0.23 ± 0.05^bc

< 0.001

0.304

0.52 ± 0.08

0.52 ± 0.07

0.68 ± 0.06

0.82 ± 0.12

0.008

0.179

0.50 ± 0.03^a

0.48 ± 0.05^ab

0.39 ± 0.02^b

0.43 ± 0.02^ab

0.018

0.734

0.53 ± 0.05

0.52 ± 0.04

0.67 ± 0.08

0.53 ± 0.04

0.541

0.492

0.39 ± 0.03^b

0.31 ± 0.03^b

0.76 ± 0.10^a

0.79 ± 0.04^a

< 0.001

0.001

0.33 ± 0.06^a

0.33 ± 0.02^a

0.23 ± 0.02^ab

0.21 ± 0.02^b

0.001

0.212

0.34 ± 0.02^a

0.29 ± 0.01^a

0.18 ± 0.02^b

0.19 ± 0.01^b

< 0.001

0.764

0.23 ± 0.04^b

0.21 ± 0.08^b

0.68 ± 0.27^a

0.51 ± 0.08^ab

0.002

0.534

0.25 ± 0.04

0.28 ± 0.09

0.33 ± 0.13

0.25 ± 0.04

0.794

0.368

0.22 ± 0.01^a

0.25 ± 0.03^a

0.13 ± 0.01^b

0.16 ± 0.01^b

< 0.001

0.207

0.20 ± 0.03^a

0.19 ± 0.01^b

0.14 ± 0.01^b

0.14 ± 0.01^b

< 0.001

0.404

0.21 ± 0.11^a

0.10 ± 0.01^ab

0.09 ± 0.02^b

0.07 ± 0.01^b

< 0.001

0.526

0.18 ± 0.05^a

0.17 ± 0.08^a

0.04 ± 0.01^b

0.08 ± 0.03^ab

0.003

0.896

0.16 ± 0.01

0.15 ± 0.02

0.18 ± 0.02

0.17 ± 0.01

0.444

0.511

0.15 ± 0.03^a

0.14 ± 0.01^a

0.08 ± 0.01^b

0.08 ± 0.01^b

< 0.001

0.366

0.14 ± 0.02^ab

0.12 ± 0.01^b

0.18 ± 0.02^ab

0.19 ± 0.02^a

0.024

0.064

0.14 ± 0.03^a

0.05 ± 0.01^b

0.19 ± 0.06^a

0.25 ± 0.06^a

0.019

< 0.001

0.13 ± 0.01

0.11 ± 0.01

0.09 ± 0.02

0.14 ± 0.03

0.904

0.107

0.12 ± 0.05

0.08 ± 0.02

0.20 ± 0.07

0.21 ± 0.08

0.061

0.058

0.12 ± 0.02

0.06 ± 0.01

0.18 ± 0.02

0.25 ± 0.05

< 0.001

< 0.001

0.12 ± 0.02

0.12 ± 0.02

0.07 ± 0.01

0.06 ± 0.01

< 0.001

0.075

0.10 ± 0.01

0.20 ± 0.12

0.13 ± 0.01

0.12 ± 0.01

0.571

0.044

0.10 ± 0.02

0.09 ± 0.02

0.12 ± 0.02

0.13 ± 0.03

0.178

0.457

0.08 ± 0.01

0.11 ± 0.04

0.09 ± 0.02

0.10 ± 0.02

0.751

0.595

0.08 ± 0.01^bc

0.07 ± 0.01^c

0.15 ± 0.02^a

0.12 ± 0.01^ab

0.004

0.475