Fig. 5

The miR-183-96-182 cluster inhibits GC apoptosis. a The expression of the miR-183-96-182 cluster in HF and EAF was detected by RNA-Seq. b, c The miR-183-96-182 cluster controls GC apoptosis. GCs were transfected with mimics (mi) (c) or inhibitors (in) (d) of miR-183, miR-96 and miR-182, and the apoptosis rate was determined by flow cytometry. d, e The miR-183-96-182 cluster controls Caspase 3 expression in GCs. GCs were transfected with mimics (mi) (e) or inhibitors (in) (f) of miR-183, miR-96 and miR-182, and the protein levels of T-CASP3 and C-CASP3 were detected by western blot. The data are presented as the mean ± SEM. of at last three independent experiments. * P < 0.05. ** P < 0.01. *** P < 0.001