L. reuteri ZJ617 inhibits inflammatory and autophagy signaling pathways in gut-liver axis in piglet induced by lipopolysaccharide

Table 3 List of significantly altered metabolites in the intestine of piglets between LPS and ZJ617 + LPS groups

Metabolite	Similarity	R.T.	Mass	VIP	P value	FC
Capric acid	901.6143	22	204	2.23	0.0299	0.03
Isoleucine 1TMS	800.1796	15.4	319	2.19	0.0327	0.02
Glycerol-1-phosphate byproduct	627.0337	21.49	361	1.94	0.0396	0.18
Linoleic acid	941.0033	23.04	204	1.87	0.0415	0.09
Alanine-alanine	812.2268	21.87	204	1.60	0.0289	0.03

LPS piglets received intraperitoneal injection (i.p.) of lipopolysaccharides (25 μg/kg body weight); ZJ617 + LPS, piglets orally inoculated with ZJ617 (1 × 10¹⁰ CFU/d) for 2 weeks before i.p. injection of lipopolysaccharides (25 μg/kg body weight)
ZJ617, Lactobacillus reuteri ZJ617; FC, fold-change of the peak intensity for the LPS group against the LPS + ZJ617 group (n = 6)
P values were calculated according to Student’s t test. Metabolites with VIP > 1.5 are shown in the table; RT, retention time; VIP, variable importance in projection

ISSN: 2049-1891