Fig. 2
From: Fibroblast growth factor 21 in dairy cows: current knowledge and potential relevance
Hypothetical model of the relevance of FGF21 in dairy cows. Formation of FGF21 in dairy cows might be mainly induced by energy deprivation and stress. FGF21 might stimulate the release of energy substrates as a metabolic adaptation to combat energy deprivation and stress conditions. High concentrations of FGF21 could impair fertility and influence the release of calcium from bone which is mainly relevant during early lactation. FGF21 might also be involved in the development of postpartal diseases, such as fatty liver and ketosis. For references, see text