Dietary resveratrol attenuation of intestinal inflammation and oxidative damage is linked to the alteration of gut microbiota and butyrate in piglets challenged with deoxynivalenol

Table 8 Effects of resveratrol on short-chain fatty acid and gut microbiota in the colon digesta of weaned piglets challenged with deoxynivalenol^a

Variable	Treatments				SEM	P-value
Variable	CON	DON	RES	DON+ RES	SEM	DON	RES	DON×RES
Relative abundance of total sequences at the genus level, %
Lactobacillus	9.77^a	1.05^b	1.57^b	4.79^ab	1.96	0.266	0.172	0.005
Faecalibacterium	2.49	1.47	7.60	4.18	1.09	0.489	0.001	0.285
Bacteroides	0.42^c	2.25^a	0.66^c	0.42^b	0.17	0.001	0.001	0.001
Roseburia	0.90^b	0.42^c	3.29^a	1.35^b	0.37	0.002	0.001	0.048
Unidentified-Enterobacteriaceae	0.12^b	1.05^a	0.13^b	0.07^b	0.05	0.001	0.001	0.001
SCFAs concentrations in the colon digesta, μg/g digesta
Acetate	194.18	204.19	190.72	192.28	12.14	0.638	0.531	0.731
Propionate	151.51	150.65	150.14	145.12	10.49	0.785	0.749	0.847
Butyrate	105.56^ab	70.52^c	110.91^a	95.75^b	4.93	<0.001	0.003	0.046

^aValues are means and standard error of the means, n = 8 per treatment; labeled means in a row without a common letter differ, P ≤ 0.05; CON Control, DON Deoxynivalenol, DON+RES Combination of deoxynivalenol and resveratrol, RES Resveratrol, SCFA Short-chain fatty acid, SEM Standard error of the mean

ISSN: 2049-1891