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Fig. 9 | Journal of Animal Science and Biotechnology

Fig. 9

From: Differential transcriptional regulation of the NANOG gene in chicken primordial germ cells and embryonic stem cells

Fig. 9

A model illustrating regulation of chicken NANOG (cNANOG) gene transcription in chicken primordial germ cells (PGCs) and embryonic stem cells (ESCs). cNANOG gene expression requires transcriptional trans-regulatory elements that are positively controlled by POU5F3 and SOX2 and negatively controlled by TP53 in PGCs. On the other hand, CCAAT/enhancer-binding protein (CEBP) positively regulates cNANOG gene expression in ESCs

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Journal of Animal Science and Biotechnology

ISSN: 2049-1891