Table 3 The effect of dietary LNT supplementation and/or RV challenge on mRNA expressions of host defense peptides and immune-related genes in the jejunal mucosa of weaned pigs

pBD1

1.00 ± 0.09^b

1.22 ± 0.03^a

0.45 ± 0.04^d

0.79 ± 0.05^c

< 0.05

< 0.05

0.30

pBD2

1.00 ± 0.06^a

1.13 ± 0.07^a

0.51 ± 0.05^c

0.79 ± 0.03^b

<  0.05

<  0.05

0.20

pBD3

1.00 ± 0.09^b

1.27 ± 0.06^a

0.58 ± 0.02^c

0.94 ± 0.05^b

< 0.05

< 0.05

0.52

pBD3

1.00 ± 0.09^b

1.27 ± 0.06^a

0.58 ± 0.02^c

0.94 ± 0.05^b

<  0.05

<  0.05

0.52

TLR3

1.00 ± 0.12^b

1.75 ± 0.10^a

1.69 ± 0.25^a

1.89 ± 0.21^a

< 0.05

< 0.05

0.18

RIG-1

1.00 ± 0.09^c

1.14 ± 0.09^bc

1.34 ± 0.09^ab

1.94 ± 0.23^a

<  0.05

<  0.05

0.12

MDA5

1.00 ± 0.09^b

1.49 ± 0.17^ab

1.61 ± 0.16^a

1.97 ± 0.25^a

< 0.05

< 0.05

0.72

MAVS

1.00 ± 0.05^b

2.21 ± 0.16^a

2.07 ± 0.19^a

2.32 ± 0.21^a

<  0.05

<  0.05

<  0.05

IFN-β

1.00 ± 0.06^c

1.42 ± 0.15^b

1.57 ± 0.08^b

2.13 ± 0.18^a

< 0.05

< 0.05

0.59

ISG-15

1.00 ± 0.10^c

1.34 ± 0.15^bc

1.85 ± 0.25 ^ab

2.41 ± 0.26^a

<  0.05

<  0.05

0.58