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Table 1 Milk yield and composition, dry matter intake, and body weight and body condition of cows supplemented with a Saccharomyces cerevisiae fermentation product (NTK) or a control diet (CON) subjected to an intramammary inflammation challenge with Streptococcus uberis. Data are separated according to experimental period: treatment feeding (Phase 1; 0–44 d), bacterial inoculation and challenge (Phase 2; 45–53 d), post antibiotic recovery (Phase 3; 54–75 d)

From: Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows

Parameterb TRTa SEM P-value
CON NTK TRT Time TRT×Time
Phase 1
 Milk yield (daily), kg 35.98 36.33 1.22 0.84 <.0001 0.93
 Milk yield (cumulative), kg 1571 1645 152 0.73
 DMI, kg DM 23.73 24.30 0.63 0.53 0.001 0.95
 DMI, % BW 1.44 4.46 0.04 0.69 0.001 0.98
 BW, kg 754.3 759 4.7 0.49 <.0001 0.02
 BCS 2.62 2.78 0.06 0.07 0.002 0.14
 Fat, % 3.82 3.78 0.14 0.83 0.0002 0.35
 Protein, % 3.69 3.72 0.03 0.54 0.01 0.15
 Lactose, % 4.79 4.89 0.02 0.18 0.08 0.48
 Solids, % 12.41 12.51 0.17 0.67 0.002 0.17
 MUN, % 12.22 12.84 0.43 0.31 0.14 0.96
 SCS 1.75 1.60 0.27 0.71 <.0001 0.45
Phase 2
 Milk yield (daily), kg 26.44 30.17 2.91 0.38 <.0001 0.08
 Milk yield (by milking), kg 8.82 10.60 1.06 0.25 <.0001 0.01
 Milk yield (cumulative), kg 160.9 196.5 19.7 0.22
 DMI, kg DM 22.21 23.27 1.13 0.51 0.04 0.11
 DMI, % BW 1.35 1.37 0.09 0.84 0.01 0.45
 BW, kg 742.6 759.2 29.9 0.69
 BCS 2.72 2.80 0.22 0.77
Phase 3
 Milk yield (daily), kg 27.54 32.84 3.35 0.28 0.0002 0.71
 Milk yield (cumulative), kg 593.6 704.4 74.6 0.31
 DMI, kg DM 22.04 22.47 1.50 0.85 0.46 0.11
 DMI, % BW 1.31 1.32 0.10 0.96 0.50 0.08
 BW, kg 766.6 773.7 16.8 0.77 0.89 0.95
 BCS 2.75 2.92 0.15 0.43 0.74 0.15
 Fatc, %
 Protein, % 3.91 3.72 0.15 0.39 0.68 0.76
 Lactose, % 4.71 4.75 0.03 0.35 0.49 0.08
 Solids, % 11.97 11.49 0.38 0.39 0.44 0.95
 MUN, % 10.35 10.24 1.13 0.94 0.05 0.91
 SCS 2.86 2.65 0.52 0.78 0.006 0.74
  1. aTRT Treatment, CON Control, NTK NutriTek® supplemented group (19 g/d)
  2. bDMI Dry matter intake, BW Body weight, BCS Body condition score, MUN Milk urea nitrogen, SCS Somatic cell score, calculated as log2(SCC/100,000) + 3, were SCC (somatic cell count) was expressed in unit of cells per microliter
  3. cPhase 3 fat content is not reported due to missing samples during shipping for analysis that reduced the n per group and prevented the model to converge