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Table 1 Milk yield and composition, dry matter intake, and body weight and body condition of cows supplemented with a Saccharomyces cerevisiae fermentation product (NTK) or a control diet (CON) subjected to an intramammary inflammation challenge with Streptococcus uberis. Data are separated according to experimental period: treatment feeding (Phase 1; 0–44 d), bacterial inoculation and challenge (Phase 2; 45–53 d), post antibiotic recovery (Phase 3; 54–75 d)

From: Feeding a Saccharomyces cerevisiae fermentation product improves udder health and immune response to a Streptococcus uberis mastitis challenge in mid-lactation dairy cows

Parameterb

TRTa

SEM

P-value

CON

NTK

TRT

Time

TRT×Time

Phase 1

 Milk yield (daily), kg

35.98

36.33

1.22

0.84

<.0001

0.93

 Milk yield (cumulative), kg

1571

1645

152

0.73

–

–

 DMI, kg DM

23.73

24.30

0.63

0.53

0.001

0.95

 DMI, % BW

1.44

4.46

0.04

0.69

0.001

0.98

 BW, kg

754.3

759

4.7

0.49

<.0001

0.02

 BCS

2.62

2.78

0.06

0.07

0.002

0.14

 Fat, %

3.82

3.78

0.14

0.83

0.0002

0.35

 Protein, %

3.69

3.72

0.03

0.54

0.01

0.15

 Lactose, %

4.79

4.89

0.02

0.18

0.08

0.48

 Solids, %

12.41

12.51

0.17

0.67

0.002

0.17

 MUN, %

12.22

12.84

0.43

0.31

0.14

0.96

 SCS

1.75

1.60

0.27

0.71

<.0001

0.45

Phase 2

 Milk yield (daily), kg

26.44

30.17

2.91

0.38

<.0001

0.08

 Milk yield (by milking), kg

8.82

10.60

1.06

0.25

<.0001

0.01

 Milk yield (cumulative), kg

160.9

196.5

19.7

0.22

–

–

 DMI, kg DM

22.21

23.27

1.13

0.51

0.04

0.11

 DMI, % BW

1.35

1.37

0.09

0.84

0.01

0.45

 BW, kg

742.6

759.2

29.9

0.69

–

–

 BCS

2.72

2.80

0.22

0.77

–

–

Phase 3

 Milk yield (daily), kg

27.54

32.84

3.35

0.28

0.0002

0.71

 Milk yield (cumulative), kg

593.6

704.4

74.6

0.31

–

–

 DMI, kg DM

22.04

22.47

1.50

0.85

0.46

0.11

 DMI, % BW

1.31

1.32

0.10

0.96

0.50

0.08

 BW, kg

766.6

773.7

16.8

0.77

0.89

0.95

 BCS

2.75

2.92

0.15

0.43

0.74

0.15

 Fatc, %

–

–

–

–

–

–

 Protein, %

3.91

3.72

0.15

0.39

0.68

0.76

 Lactose, %

4.71

4.75

0.03

0.35

0.49

0.08

 Solids, %

11.97

11.49

0.38

0.39

0.44

0.95

 MUN, %

10.35

10.24

1.13

0.94

0.05

0.91

 SCS

2.86

2.65

0.52

0.78

0.006

0.74

  1. aTRT Treatment, CON Control, NTK NutriTek® supplemented group (19 g/d)
  2. bDMI Dry matter intake, BW Body weight, BCS Body condition score, MUN Milk urea nitrogen, SCS Somatic cell score, calculated as log2(SCC/100,000) + 3, were SCC (somatic cell count) was expressed in unit of cells per microliter
  3. cPhase 3 fat content is not reported due to missing samples during shipping for analysis that reduced the n per group and prevented the model to converge