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Fig. 6 | Journal of Animal Science and Biotechnology

Fig. 6

From: Comprehensive evaluation of the metabolic effects of porcine CRTC3 overexpression on subcutaneous adipocytes with metabolomic and transcriptomic analyses

Fig. 6

Working model of the metabolic effects of CRTC3 on porcine subcutaneous adipocytes. Using a combination of transcriptomic and metabolomic analyses, overexpression of CRTC3 was shown to activate C/EBPα, the cAMP/PKA and FA metabolism and other signaling pathways to regulate adipogenesis, lipolysis and FA metabolism and subsequently induce lipid accumulation and metabolic changes in porcine adipocytes. Arrows with a dashed line indicate that the regulatory effect must be confirmed, arrows with a solid line indicates direct regulation or a direct connection, and the orange arrow indicates the process of adipogenesis

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