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Table 2 Evaluation of copper acetate (CA), curcumin (CR) and copper acetate – curcumin (CA-CR) on cecal tonsils (CT) colonization of Salmonella Typhimurium1 and serum concentration of fluorescein isothiocyanate-dextran (FITC-d) in broiler chickens on day ten post-S. Typhimurium challenge2 in trial 1 and trial 2

From: Evaluation of curcumin and copper acetate against Salmonella Typhimurium infection, intestinal permeability, and cecal microbiota composition in broiler chickens

Treatments

CT, log10 CFU/g

FITC-d, ng/mL

 

Trial 1

CTRL (−)

0.00 ± 0.00 d

17.03 ± 5.44 b

CTRL (+)

6.18 ± 0.33 a

54.99 ± 10.51 a

CA

4.99 ± 0.32 b

35.19 ± 8.80 ab

CR

3.92 ± 0.55 bc

17.60 ± 7.50 b

CA-CR

3.76 ± 0.54 c

32.99 ± 10.34 ab

SEM3

0.33

4.18

P-value

0.000

0.020

 

Trial 2

CTRL (−)

0.00 ± 0.00 d

19.80 ± 9.26 b

CTRL (+)

6.09 ± 0.276 a

59.38 ± 9.81 a

CA

4.94 ± 0.32 b

32.99 ± 11.31 ab

CR

3.91 ± 0.19 c

15.40 ± 7.60 b

CA-CR

3.78 ± 0.31 c

39.59 ± 15.06 ab

SEM3

0.30

5.13

P-value

0.000

0.048

  1. 1 Data expressed in log10 CFU/g of tissue. Mean ± SE from 12 chickens. a–d Values within treatments columns for each treatment with different superscripts differ significantly (P < 0 .05)
  2. 2 Chickens were orally gavaged with 104 CFU of S. Typhimurium per chicken at 1 day old, samples were collected at day 10 post-challenge
  3. 3 Standard error of the means