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Table 6 Plasma concentrations of amino acids and amino acid metabolites of pigs fed isonitrogenous diets without (CON) or with 5% insect meal (IM5) or 10% insect meal (IM10) for 4 weeks

From: Comprehensive evaluation of the metabolic effects of insect meal from Tenebrio molitor L. in growing pigs by transcriptomics, metabolomics and lipidomics

 

CON

IM5

IM10

P-value

Amino acids, μmol/L

 Alanine

725 ± 74b

720 ± 95b

860 ± 88a

0.002

 Arginine

191 ± 32

191 ± 39

175 ± 40

0.532

 Asparagine

101.3 ± 19.4a

89.2 ± 18.3ab

77.1 ± 14.3b

0.017

 Aspartate

27.8 ± 4.5

27.0 ± 8.2

29.4 ± 5.7

0.704

 Citrulline

80.4 ± 14.6b

78.8 ± 8.7b

92.8 ± 12.9a

0.038

 Glutamine

775 ± 86

741 ± 129

746 ± 104

0.747

 Glutamate

344 ± 36b

374 ± 138ab

457 ± 92a

0.041

 Glycine

1267 ± 148

1401 ± 235

1421 ± 252

0.241

 Histidine

37.6 ± 11.9

43.0 ± 11.4

38.1 ± 9.1

0.485

 Isoleucine

256 ± 51

241 ± 44

242 ± 30

0.693

 Leucine

180 ± 48

213 ± 36

202 ± 39

0.219

 Lysine

499 ± 47

545 ± 141

493 ± 109

0.500

 Methionine

66.9 ± 16.4

78.6 ± 20.5

65.6 ± 19.8

0.039

 Ornithine

140 ± 16

148 ± 41

139 ± 28

0.771

 Phenylalanine

81.4 ± 12.4

75.7 ± 9.6

69.2 ± 13.6

0.094

 Proline

485 ± 73b

561 ± 72a

618 ± 62a

0.001

 Serine

172 ± 26b

187 ± 26ab

204 ± 23a

0.035

 Threonine

348 ± 78

402 ± 84

388 ± 134

0.472

 Tryptophan

82.3 ± 10.3

73.8 ± 11.1

74.8 ± 13.6

0.234

 Tyrosine

129 ± 24c

161 ± 20b

188 ± 24a

0.001

 Valine

393 ± 69c

526 ± 60b

635 ± 84a

0.001

Amino acid metabolites, μmol/L

 Asymmetric dimethylarginine

1.85 ± 0.19

1.89 ± 0.18

1.94 ± 0.17

0.524

 Alpha-aminoadipic acid

49.5 ± 10.5

47.7 ± 13.3

40.1 ± 18.2

0.316

 Carnosine

17.4 ± 2.6

16.7 ± 3.8

15.8 ± 3.4

0.568

 Creatinine

70.3 ± 8.2

67.8 ± 8.1

67.4 ± 9.9

0.728

 Histamine

1.28 ± 1.17

1.01 ± 0.80

1.31 ± 0.94

0.806

 Kynurenine

0.99 ± 0.17

0.93 ± 0.12

1.00 ± 0.21

0.691

 Methionine sulfoxide

3.28 ± 0.78b

4.77 ± 1.24a

5.61 ± 1.44a

0.001

 Putrescine

1.10 ± 0.17

1.11 ± 0.24

1.17 ± 0.14

0.628

 Sarcosine

2.23 ± 0.34

2.41 ± 0.35

2.63 ± 0.56

0.140

 Symmetric dimethylarginine

0.85 ± 0.11

0.84 ± 0.09

0.92 ± 0.09

0.084

 Serotonin

0.39 ± 0.40

0.46 ± 0.38

0.47 ± 0.41

0.705

 Spermidine

0.83 ± 0.35

0.80 ± 0.37

0.68 ± 0.35

0.555

 Trans-4-hydroxyproline

115 ± 16

123 ± 14

122 ± 7

0.328

 Taurine

64.3 ± 14.9

74.7 ± 20.0

69.9 ± 16.2

0.418

  1. Values are means ± SDs for n = 10 pigs per group. Means without a common superscript letter differ, P < 0.05
  2. Abbreviations: CON control group; IM5 insect meal 5% group; IM10 insect meal 10% group