Fig. 5From: DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturationMdivi-1 treatment induces apoptosis in porcine oocytes. a Annexin-V signals in the control and treatment group oocytes. Most control oocytes exhibited weak Annexin-V fluorescence signals, while the signals were much stronger in treated oocytes. Green, Annexin-V. Bar = 20 μm. b Annexin-V fluorescence intensity analysis. Fluorescence intensity was much higher in the treatment group oocytes than the control oocytes. c BCL_x1, BAX, and caspase3 mRNA levels decreased significantly after inhibiting DRP1 in porcine oocytesBack to article page