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Fig. 4 | Journal of Animal Science and Biotechnology

Fig. 4

From: DRP1 deficiency induces mitochondrial dysfunction and oxidative stress-mediated apoptosis during porcine oocyte maturation

Fig. 4

Mdivi-1 treatment induces oxidative stress in porcine oocytes. a The reactive oxygen species (ROS) level in the control and treatment groups of oocytes. Most control oocytes revealed weak ROS fluorescence signals, while the signals were much stronger in treated oocytes. Green, ROS. Bar = 20 μm. b ROS fluorescence intensity analysis. Fluorescence intensity was much higher in the treatment group oocytes than the control oocytes. c Superoxide dismutase (SOD)1 and SOD2 mRNA levels decreased significantly while the glutathione peroxidase (GPx) mRNA level increased significantly increased after inhibiting DRP1

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