Dietary plant extracts modulate gene expression profiles in alveolar macrophages of pigs experimentally infected with porcine reproductive and respiratory syndrome virus

Table 2 Gene expression profiles changed by porcine reproductive and respiratory syndrome virus (PRRSV) infection and by dietary supplementation of plant extracts to PRRSV-infected pigs^a

Dietary supplement	Comparison^b	Up-regulated	Down-regulated	Total
PRRSV	ICON vs. CON	755	597	1,352
Capsicum oleoresin, 10 mg/kg	ICAP vs. ICON	24	22	46
Garlic botanical, 10 mg/kg	IGAR vs. ICON	59	75	134
Turmeric oleoresin, 10 mg/kg	ITUR vs. ICON	55	43	98

^aThe gene expression changed by fold-change cutoff of 1.5 and a P-value cutoff of 0.05. All data were analyzed by DAVID Bioinformatics Resources 6.7 (National Institute of Allergy and Infectious Diseases, NIH, Bethasda, MD, USA)
^bCON = uninfected control diet-fed pigs; ICAP = infected capsicum oleoresin-fed pigs; ICON = infected control diet-fed pigs; IGAR = infected garlic botanical-fed pigs; ITUR = infected turmeric oleoresin-fed pigs

ISSN: 2049-1891