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Table 5 Concentrations of acute phase and negative acute phase proteins in plasma and relative mRNA abundances of proinflammatory genes and genes of the acute phase reaction in the liver of cows fed the control diet (Con) or the diet supplemented with green tea extract (GTE) in weeks 1, 4 and 7 of lactation1

From: Effects of supplementation of green tea extract on the milk performance of peripartal dairy cows and the expression of stress response genes in the liver

 Week 1 Week 4 Week 7 P-value
ConGTESEMConGTESEMConGTESEMGTEWeekGTE × weekParity
Plasma
 SAA, μg/mL0.33a0.26b0.020.33a0.27b0.020.290.250.020.0070.0290.520.41
 HP, mg/mL0.930.830.340.370.260.330.960.500.340.590.220.670.003
 Albumin, g/dL2.832.700.142.982.870.143.083.000.140.230.0030.940.30
 RBP4, μg/mL1.591.660.151.571.640.151.761.760.150.220.080.87<  0.001
Liver, relative mRNA abundances2
CCL21.001.020.311.211.130.311.531.560.310.900.0340.960.68
IL1B1.001.200.180.861.050.180.941.000.180.650.330.780.018
CXCL81.000.960.361.361.930.361.741.660.360.480.0010.200.61
PTGS21.001.100.221.181.280.221.011.220.220.270.380.900.44
TNF1.001.480.381.381.840.381.171.390.380.360.160.780.14
CP1.000.810.160.720.770.160.840.750.160.660.230.420.49
CRP1.000.650.161.211.040.161.160.930.160.0350.0300.720.87
HP1.000.860.430.130.950.430.200.500.430.280.060.140.98
SAA31.001.290.360.540.790.360.580.630.360.460.0250.830.93
  1. 1Values are least square means, n = 15 for each group
  2. 2Relative mRNA abundances of Con in week 1 are set as a reference (=1.00)
  3. a,b Means within one week with different superscripts differ significantly (P < 0.05)
  4. HP, haptoglobin; RBP4, retinol binding protein 4; SAA, serum amyloid A; SEM, standard error of means