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Table 3 Differentially abundant KEGG pathways affected by energy levels which were detected using LEfSe with an LDA effect size ≥2.0

From: Dietary energy sources and levels shift the multi-kingdom microbiota and functions in the rumen of lactating dairy cows

Item EC numbers Relative abundance, % SEM Class LDA score P-value Description
LE HE
Prokaryotic EC 1.2.7.11 0.506 0.467 0.007 LE 2.312 0.009 2-oxoacid oxidoreductase (ferredoxin)
EC 1.2.7.3 0.762 0.704 0.011 LE 2.483 0.013 2-oxoglutarate synthase
EC 1.3.5.1 0.271 0.248 0.004 LE 2.075 0.001 Succinate dehydrogenase (quinone)
EC 1.6.5.3 1.333 1.279 0.010 LE 2.424 0.006 NADH:ubiquinone reductase (H+-translocating)
EC 2.7.7.13 0.291 0.270 0.004 LE 2.025 0.011 Mannose-1-phosphate guanylyltransferase
EC 3.2.1.23 0.585 0.549 0.008 LE 2.249 0.020 Beta-galactosidase
EC 3.2.1.51 0.382 0.352 0.006 LE 2.175 0.013 Alpha-L-fucosidase
EC 3.4.21.102 0.400 0.377 0.004 LE 2.062 0.003 C-terminal processing peptidase
EC 5.2.1.8 1.219 1.185 0.008 LE 2.195 0.018 Peptidylprolyl isomerase
EC 5.4.99.2 0.181 0.156 0.004 LE 2.104 0.001 Methylmalonyl-CoA mutase
EC 2.2.1.6 0.298 0.324 0.004 HE 2.130 0 Acetolactate synthase
EC 2.3.1.15 0.094 0.115 0.004 HE 2.037 0.004 Glycerol-3-phosphate 1-O-acyltransferase
EC 2.7.1.69 0.141 0.181 0.011 HE 2.303 0.009 Protein-N(pi)-phosphohistidine-sugar phosphotransferase
EC 2.7.13.3 0.477 0.513 0.009 HE 2.247 0.009 Histidine kinase
EC 3.4.16.4 0.261 0.286 0.003 HE 2.075 0 Serine-type D-Ala-D-Ala carboxypeptidase
EC 3.6.3.17 0.108 0.128 0.006 HE 2.002 0.011 Monosaccharide-transporting ATPase
Fungal EC 2.3.1.48 1.149 1.060 0.015 LE 2.646 0.006 Histone acetyltransferase
EC 2.4.1.16 0.536 0.486 0.013 LE 2.396 0.019 Chitin synthase
EC 3.2.1.18 1.825 1.736 0.021 LE 2.659 0.010 Exo-alpha-sialidase
EC 3.2.1.3 2.166 1.922 0.052 LE 3.088 0.024 Glucan 1,4-alpha-glucosidase
EC 4.6.1.2 0.063 0.042 0.007 LE 2.025 0.032 Guanylate cyclase
EC 5.2.1.8 1.883 1.756 0.030 LE 2.803 0.012 Peptidylprolyl isomerase
EC 1.14.13.12 0.077 0.123 0.011 HE 2.381 0.042 Benzoate 4-monooxygenase
EC 2.3.1.85 0.036 0.060 0.006 HE 2.104 0.035 Fatty-acid synthase
EC 3.1.1.3 0.509 0.530 0.005 HE 2.035 0.029 Triacylglycerol lipase
EC 3.2.1.58 0.486 0.539 0.012 HE 2.419 0.003 Glucan 1,3-beta-glucosidase
EC 3.4.17.21 0.149 0.172 0.005 HE 2.043 0.013 Glutamate carboxypeptidase II
EC 3.5.1.4 0.271 0.305 0.010 HE 2.244 0.046 Amidase
EC 4.1.1.1 0.129 0.155 0.004 HE 2.104 0.001 Pyruvate decarboxylase
  1. LE Low energy, HE High energy
  2. No functional features were differed by energy sources