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Table 4 Effect of E. faecium on cytokines concentrations in the plasma and ileal mucosa of piglets challenged with ETEC K88

From: Enterococcus faecium NCIMB 10415 administration improves the intestinal health and immunity in neonatal piglets infected by enterotoxigenic Escherichia coli K88

Items -ETEC +ETEC P-value
CON PRO CON PRO PRO ETEC PRO×ETEC
Plasma
 IL-1β, ng/mL 0.78 ± 0.07b 0.93 ± 0.15ab 1.32 ± 0.20a 1.13 ± 0.21ab 0.93 0.04 0.33
 IL-6, ng/mL 11.04 ± 1.25 11.07 ± 1.90 11.31 ± 1.03 12.32 ± 1.47 0.71 0.59 0.72
 TNF-α, pg/mL 49.16 ± 6.44 51.29 ± 5.42 57.20 ± 6.50 42.81 ± 4.53 0.38 0.97 0.24
Ileal mucosa
 IL-1β, ng/mL 5.22 ± 0.85 5.08 ± 0.51 5.67 ± 0.92 5.87 ± 0.75 0.97 0.45 0.83
 IL-6, ng/mL 9.22 ± 0.74 10.30 ± 0.42 11.04 ± 0.59 10.84 ± 0.79 0.54 0.11 0.37
 TNF-α, ng/mL 0.90 ± 0.06b 0.88 ± 0.06b 1.15 ± 0.07a 1.02 ± 0.06ab 0.25 < 0.01 0.41
  1. Data are presented as means ± SE (n = 8)
  2. -ETEC, infusing the essential medium; +ETEC, infusing the Escherichia coli; CON, control group; PRO, Enterococcus faecium-supplemented group
  3. a, bMeans within a row with different superscripts are significantly different (P < 0.05)