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Table 4 Effect of E. faecium on cytokines concentrations in the plasma and ileal mucosa of piglets challenged with ETEC K88

From: Enterococcus faecium NCIMB 10415 administration improves the intestinal health and immunity in neonatal piglets infected by enterotoxigenic Escherichia coli K88

Items

-ETEC

+ETEC

P-value

CON

PRO

CON

PRO

PRO

ETEC

PRO×ETEC

Plasma

 IL-1β, ng/mL

0.78 ± 0.07b

0.93 ± 0.15ab

1.32 ± 0.20a

1.13 ± 0.21ab

0.93

0.04

0.33

 IL-6, ng/mL

11.04 ± 1.25

11.07 ± 1.90

11.31 ± 1.03

12.32 ± 1.47

0.71

0.59

0.72

 TNF-α, pg/mL

49.16 ± 6.44

51.29 ± 5.42

57.20 ± 6.50

42.81 ± 4.53

0.38

0.97

0.24

Ileal mucosa

 IL-1β, ng/mL

5.22 ± 0.85

5.08 ± 0.51

5.67 ± 0.92

5.87 ± 0.75

0.97

0.45

0.83

 IL-6, ng/mL

9.22 ± 0.74

10.30 ± 0.42

11.04 ± 0.59

10.84 ± 0.79

0.54

0.11

0.37

 TNF-α, ng/mL

0.90 ± 0.06b

0.88 ± 0.06b

1.15 ± 0.07a

1.02 ± 0.06ab

0.25

< 0.01

0.41

  1. Data are presented as means ± SE (n = 8)
  2. -ETEC, infusing the essential medium; +ETEC, infusing the Escherichia coli; CON, control group; PRO, Enterococcus faecium-supplemented group
  3. a, bMeans within a row with different superscripts are significantly different (P < 0.05)