Dietary supplementation of Bacillus subtilis influenced intestinal health of weaned pigs experimentally infected with a pathogenic E. coli

Table 2 Growth performance of weaned pigs fed diets supplemented with Bacillus subtilis

Item^d	E. coli challenge				SEM	P-value
Item^d	Negative control	Positive control	Low dose Bacillus subtilis	High dose Bacillus subtilis	SEM	Diet	Lin.^e	Quad.^e
BW, kg
d – 7^f	6.76	6.76	6.64	6.73	0.23	0.73	0.82	0.32
d 0^f	7.98	7.78	7.84	7.91	0.59	0.87	0.61	0.99
d 5 PI^g	9.52^a	8.41^b	8.83^ab	9.06^ab	0.60	0.039	0.086	0.76
d 11 PI^g	12.93	11.02	11.92	12.56	1.67	0.14	0.084	0.86
ADG, g
d − 7 to 0^f	174	146	167	168	77.33	0.83	0.50	0.72
d 0 to 5 PI^f	308^a	125^c	193^bc	230^ab	40.79	< 0.01	0.036	0.71
d 5 to 11 PI^g	426	373	435	452	129.5	0.73	0.31	0.73
d 0 to 11 PI^g	416^a	272^b	340^ab	375^ab	74.45	0.057	0.058	0.71
ADFI, g
d − 7 to 0^f	308	311	303	271	57.66	0.74	0.33	0.73
d 0 to 5 PI^f	572^a	365^b	386^b	423^ab	58.29	< 0.01	0.21	0.85
d 5 to 11 PI^g	637	585	566	735	96.61	0.24	0.095	0.24
d 0 to 11 PI^g	617	507	459	603	48.76	0.11	0.16	0.13
G:F
d − 7 to 0^f	0.58	0.42	0.50	0.57	0.171	0.13	0.051	0.99
d 0 to 5 PI^f	0.52	0.35	0.45	0.52	0.078	0.32	0.11	0.82
d 5 to 11 PI^g	0.67	0.61	0.74	0.60	0.150	0.47	0.90	0.14
d 0 to 11 PI^g	0.68^a	0.52^b	0.71^a	0.59^ab	0.127	0.084	0.36	0.034

^a-cMeans without a common superscript are different (P < 0.05); bold P values denote statistical significance at the P < 0.05
^dBW body weight, ADG average daily gain, ADFI average daily feed intake, G:F gain:feed, PI post inoculation
^eLinear and quadratic effects of adding Bacillus subtilis to the control diet in pigs infected with F18 E. coli
^fEach least squares mean represents 12 observations
^gEach least squares mean represents 6 observations

ISSN: 2049-1891