Parameter | IPF | GPF | P-value2 | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
70 | 85 | 100 | 115 | 130 | 70 | 85 | 100 | 115 | 130 | MSE1 | L | FS | L × FS | |
Number of observations | 10 | 8 | 11 | 10 | 10 | 11 | 10 | 11 | 11 | 11 | ||||
Urea, μmol/L | 2.70 | 1.98 | 2.38 | 2.19 | 2.77 | 2.74 | 2.04 | 2.34 | 2.07 | 2.40 | 0.23 | < 0.01‡ | 0.51 | 0.83 |
Albumin, g/L | 27.80 | 26.56 | 32.12 | 31.59 | 33.51 | 29.50 | 31.44 | 32.25 | 31.63 | 31.19 | 1.25 | < 0.01† | 0.19 | 0.03 |
Creatinine, μmol/L | 116.85 | 114.69 | 112.68 | 110.85 | 117.50 | 117.50 | 116.91 | 115.35 | 112.41 | 119.41 | 3.69 | 0.25 | 0.39 | 1.00 |
Lactic acid dehydrogenase, U/L | 585.34 | 581.88 | 535.13 | 532.60 | 570.35 | 524.96 | 485.73 | 537.90 | 468.60 | 557.14 | 47.66 | 0.53 | 0.06 | 0.72 |
Total protein, g/L | 62.65 | 64.26 | 65.33 | 66.90 | 67.48 | 61.86 | 65.56 | 64.37 | 66.00 | 66.13 | 1.52 | 0.01† | 0.52 | 0.89 |
Aspartate aminotransferase, U/L | 36.75 | 44.96 | 38.35 | 43.80 | 43.09 | 36.89 | 37.50 | 36.60 | 36.48 | 44.21 | 3.50 | 0.08† | 0.08 | 0.34 |
Alanine aminotransferase, U/L | 47.50 | 40.79 | 39.73 | 40.00 | 38.39 | 41.14 | 45.05 | 44.37 | 36.06 | 43.90 | 3.03 | 0.14 | 0.60 | 0.04a,b |
Creatine kinase, U/L | 1083 | 1561 | 1227 | 1822 | 1918 | 1108 | 1244 | 1562 | 1015 | 2172 | 412 | 0.15 | 0.67 | 0.52 |
Immunoglobulin G, μg/mL | 11.29 | 11.28 | 9.93 | 11.90 | 10.98 | 9.71 | 10.90 | 9.48 | 11.31 | 11.36 | 1.18 | 0.19 | 0.33 | 0.84 |
C-reactive protein, μg/mL | 9.25 | 13.02 | 9.98 | 18.35 | 24.78 | 13.88 | 15.81 | 18.46 | 22.82 | 12.68 | 3.56 | 0.05† | 0.26 | 0.01a,c |