Table 3 KEGG Pathways and Gene ontologies (GO category) of mRNA transcripts differentially expressed in cows treated with estradiol cypionate (ECP).
Category | Term | Count | P value | Genes |
|---|---|---|---|---|
Upregulated in ECP | ||||
KEGG PATHWAY | Pathways in cancer | 5 | 0.008 | PIK3R3, PTCH1, PTCH2, LAMC3, PIAS1 |
KEGG PATHWAY | Small cell lung cancer | 3 | 0.020 | PIK3R3, LAMC3, PIAS1 |
GO TERM BP_FAT | Epidermis development | 2 | 0.095 | ADAM9, ENSBTAG00000017455 |
Downregulated in ECP | ||||
KEGG PATHWAY | Parkinson’s disease | 3 | 0.062 | NDUFB3, ATP5F1, ATP5J |
KEGG PATHWAY | Oxidative phosphorylation | 3 | 0.064 | NDUFB3, ATP5F1, ATP5J |
KEGG PATHWAY | Alzheimer’s disease | 3 | 0.090 | NDUFB3, ATP5F1, ATP5J |
GO TERM BP_FAT | Generation of precursor metabolites and energy | 5 | 0.004 | GPI, NDUFB3, ATP5F1, IDH3B, ATP5J |
GO TERM BP_FAT | Translation | 4 | 0.059 | RPS2, EEF1D, ENSBTAG00000013866, ENSBTAG00000011263 |
GO TERM BP_FAT | mRNA processing | 3 | 0.071 | GEMIN7, SNRPD2, STRAP |
GO TERM BP_FAT | mRNA metabolic process | 3 | 0.087 | GEMIN7, SNRPD2, STRAP |
GO TERM BP_FAT | RNA splicing | 3 | 0.041 | GEMIN7, SNRPD2, STRAP |