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Table 2 Individual measurements of IL-1β concentration (pg/mL) in blood plasma and cerebrospinal fluid (CSF) in sham-implanted and melatonin implanted ewes before and 3 h after lipopolysaccharide (LPS, 400 ng/kg) administration

From: Plasma and cerebrospinal fluid interleukin-1β during lipopolysaccharide-induced systemic inflammation in ewes implanted or not with slow-release melatonin

Sham-implanted Melatonin-implanted
  Plasma, pg/mL CSF, pg/mL   Plasma, pg/mL CSF, pg/mL
Ewe # Before After LPS Before After LPS Ewe # Before After LPS Before After LPS
1 0.0 65.3 27.8 48.0 1 143.3 211.0 26.4 410.8
2 0.0 105.9 13.5 35.5 2 128. 134.7 67.4 146.5
3 53.0 58.5 21.0 50.4 3 0.0 210.7 19,2 39.6
4 76.1 113.0 20.3 365.6 4 0.0 298.4 0.0 198.5
5 197.2 399.0 22.8 66.7 5 0.0 80.3 0.0 12.3
6 49.4 214.2 51.7 213.7 6 192.7 378.7 24.2 54.0
      7 0.0 71.0 11,8 115.4
Mean (±SEM) 62.0 (±29.7) 159.3a (±53.1) 26.2 (±5.4) 129.8a (±54.2)   66.4 (±32.1) 197.8a (±42.8) 21.3 (±8.7) 139.6a (±51.5)
  1. asignificant vs. concentration before LPS administration at P < 0.05