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Table 1 Branched chain amino acids and immune function

From: Novel metabolic and physiological functions of branched chain amino acids: a review

Amino acid Regulation of immune function
BCAA Mix ↑ fuel sources for immune cells
↑ immune function of neutrophils and lymphocytes
↑ CD4+, CD4+/CD8+
↑ intestinal immunoglobulins
Isoleucine ↑ excretion of β-defensin
Leucine ↑ regulation of innate and adaptive immune responses
↑ pro-inflammatory cytokines ↓ anti-inflammatory cytokines
Valine ↑ dendritic cell function
↑ pro-inflammatory cytokines ↓ anti-inflammatory cytokines