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Table 5 Effects of the SNPs on SCS and cytokines of Chinese Holstein and Sanhe cattle

From: Novel SNPs in IL-17F and IL-17A genes associated with somatic cell count in Chinese Holstein and Inner-Mongolia Sanhe cattle

SNPs Breed Genotype, n SCS IL-4, IL-6, IL-17, IFN-γ, TNF-α,
ng/mL pg/mL pg/mL pg/mL pg/mL
IL-17 F Holstein CC (228) 5.93 ± 0.47a 1.105 ± 0.056 174.87 ± 6.80 14.44 ± 0.82 46.58 ± 2.00 1.16 ± 0.05
g.24392436 C > T   CT (91) 4.96 ± 0.55b 1.153 ± 0.062 179.86 ± 7.56 14.47 ± 0.91 44.44 ± 2.22 1.15 ± 0.06
   TT (16) 4.60 ± 0.92b 1.182 ± 0.101 175.49 ± 12.29 17.09 ± 1.48 45.53 ± 3.62 1.09 ± 0.09
   P value <0.05 0.50 0.70 0.17 0.47 0.79
  Sanhe CC(76) 4.14 ± 0.81 0.91 ± 0.067 107.27 ± 9.80 12.38 ± 2.10A 37.06 ± 3.36 1.06 ± 0.090
   CT(38) 4.31 ± 0.86 0.93 ± 0.071 109.09 ± 10.46 10.99 ± 2.24A 36.28 ± 3.59 1.03 ± 0.096
   TT(9) 4.10 ± 1.08 0.92 ± 0.089 118.35 ± 13.06 17.68 ± 2.87B 37.60 ± 4.48 0.95 ± 0.12
   P value 0.9 0.94 0.62 <0.01 0.87 0.41
IL-17A Holstein AA (51) 5.51 ± 0.60 1.026 ± 0.070B 179.33 ± 8.58 14.05 ± 1.04 43.96 ± 2.52 1.15 ± 0.07
g.24345410 A > G   AG (149) 5.71 ± 0.51 1.190 ± 0.057A 173.45 ± 7.05 15.12 ± 0.85 46.29 ± 2.07 1.13 ± 0.06
   GG (137) 5.35 ± 0.51 1.105 ± 0.058a 178.59 ± 7.17 14.55 ± 0.87 46.13 ± 2.11 1.16 ± 0.06
   P value 0.73 <0.05 0.59 0.46 0.55 0.79
  Sanhe AA(36) 4.65 ± 0.82 0.872 ± 0.067b 104.20 ± 9.99 11.67 ± 2.24 35.80 ± 3.46 1.04 ± 0.094
   AG(42) 3.77 ± 0.82 0.965 ± 0.066a 108.42 ± 9.94 11.86 ± 2.23 37.64 ± 3.44 1.08 ± 0.093
   GG(45) 4.19 ± 0.85 0.905 ± 0.069ab 115.65 ± 10.39 13.67 ± 2.34 37.72 ± 3.60 1.03 ± 0.097
   P value 0.14 <0.05 0.09 0.18 0.51 0.56
  1. Means with different superscripts within the same column and breed are significantly different at P < 0.01 (capital letter) or P < 0.05 (small letter)