Journal of Animal Science and Biotechnology

Table 4 Effect of supplementing AGP, feed enzymes (ENZ) or yeast extract (YE) without or with ENZ on PUN (mmol/L) and count of white blood cells (WBC, 10⁹/L), red blood cells (RBC, 10¹²/L) and platelets (10⁹/L) of weaned piglets challenged with E. coli LPS

From: Short-term effect of supplemental yeast extract without or with feed enzymes on growth performance, immune status and gut structure of weaned pigs challenged with Escherichia coli lipopolysaccharide

		LPS treatments^b						Factorial^c			Contrast
Item	NCC^a	AGP	CC	YE	ENZ	YE + ENZ	SEM	Main effect YE	Main effect ENZ	YE × ENZ	NCC vs CC	AGP vs CC	AGP vs YE	AGP vs ENZ	AGP vs YE + ENZ
PUN
Pre-challenge	2.34	2.28	2.95	2.08	2.52	2.57	0.412	NS	NS	NS	NS	NS	NS	NS	NS
6 h post-challenge	2.12	2.58	4.18	2.5	3.42	2.6	0.478	0.03	NS	NS	0.01	0.02	NS	NS	NS
48 h post-challenge	2.16	1.93	2.97	1.24	1.6	1.83	0.285	0.01	NS	0.001	0.08	0.02	0.07	NS	NS
96 h post-challenge	1.66	1.78	3.2	2.1	2.55	2.77	0.384	NS	NS	0.057	0.01	0.02	NS	NS	0.09
WBC
Pre-challenge	16.9	18	17.8	15	14.1	19.3	2.21	NS	NS	0.062	NS	NS	NS	NS	NS
6 h post-challenge	19.7	10.2	6.5	12.2	7.6	15.5	1.98	0.003	NS	NS	0.0004	NS	NS	0.07	0.07
48 h post-challenge	18.2	16.8	17.3	17.5	16.2	19.7	1.68	NS	NS	NS	NS	NS	NS	NS	NS
96 h post-challenge	19.6	16.7	16.9	16.3	14.5	18.2	1.3	NS	NS	NS	NS	NS	NS	NS	NS
RBC
Pre-challenge	5.96	5.54	6.04	6.09	6.04	6.06	0.228	NS	NS	NS	NS	NS	NS	NS	NS
6 h post-challenge	5.91	5.68	6.01	6.62	6.33	5.97	0.255	NS	NS	0.090	NS	NS	0.01	NS	NS
48 h post-challenge	5.59	4.96	5.39	5.41	5.48	5.25	0.184	NS	NS	NS	NS	NS	0.07	NS	NS
96 h post-challenge	5.95	5.18	5.32	5.6	5.46	5.22	0.19	NS	NS	NS	0.02	NS	NS	NS	NS
Platelet
Pre-challenge	429	534	450	483	447	415	44.8	NS	NS	NS	NS	NS	NS	NS	NS
6 h post-challenge	413	309	196	350	205	278	37.3	0.001	NS	NS	0.0002	0.04	NS	NS	NS
48 h post-challenge	445	345	350	338	322	345	29.9	NS	NS	NS	0.05	NS	NS	NS	NS
96 h post-challenge	449	446	386	520	427	507	61.3	0.06	NS	NS	NS	NS	NS	NS	NS

^a NCC non-challenged control pigs that were fed the basal diet and injected with sterile saline on d 7
^bPigs fed the basal diet without any additive (CC challenged control) or with AGP, YE, ENZ or ENZ + YE and injected with E. coli LPS on d 7
^c P-value for LPS + ENZ × LPS + YE interaction (CC, YE, ENZ and ENZ + YE)

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ISSN: 2049-1891

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