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Table 4 Effect of supplementing AGP, feed enzymes (ENZ) or yeast extract (YE) without or with ENZ on PUN (mmol/L) and count of white blood cells (WBC, 109/L), red blood cells (RBC, 1012/L) and platelets (109/L) of weaned piglets challenged with E. coli LPS

From: Short-term effect of supplemental yeast extract without or with feed enzymes on growth performance, immune status and gut structure of weaned pigs challenged with Escherichia coli lipopolysaccharide

   LPS treatmentsb   Factorialc Contrast
Item NCCa AGP CC YE ENZ YE + ENZ SEM Main effect YE Main effect ENZ YE × ENZ NCC vs CC AGP vs CC AGP vs YE AGP vs ENZ AGP vs YE + ENZ
PUN
 Pre-challenge 2.34 2.28 2.95 2.08 2.52 2.57 0.412 NS NS NS NS NS NS NS NS
 6 h post-challenge 2.12 2.58 4.18 2.5 3.42 2.6 0.478 0.03 NS NS 0.01 0.02 NS NS NS
 48 h post-challenge 2.16 1.93 2.97 1.24 1.6 1.83 0.285 0.01 NS 0.001 0.08 0.02 0.07 NS NS
 96 h post-challenge 1.66 1.78 3.2 2.1 2.55 2.77 0.384 NS NS 0.057 0.01 0.02 NS NS 0.09
WBC
 Pre-challenge 16.9 18 17.8 15 14.1 19.3 2.21 NS NS 0.062 NS NS NS NS NS
 6 h post-challenge 19.7 10.2 6.5 12.2 7.6 15.5 1.98 0.003 NS NS 0.0004 NS NS 0.07 0.07
 48 h post-challenge 18.2 16.8 17.3 17.5 16.2 19.7 1.68 NS NS NS NS NS NS NS NS
 96 h post-challenge 19.6 16.7 16.9 16.3 14.5 18.2 1.3 NS NS NS NS NS NS NS NS
RBC
 Pre-challenge 5.96 5.54 6.04 6.09 6.04 6.06 0.228 NS NS NS NS NS NS NS NS
 6 h post-challenge 5.91 5.68 6.01 6.62 6.33 5.97 0.255 NS NS 0.090 NS NS 0.01 NS NS
 48 h post-challenge 5.59 4.96 5.39 5.41 5.48 5.25 0.184 NS NS NS NS NS 0.07 NS NS
 96 h post-challenge 5.95 5.18 5.32 5.6 5.46 5.22 0.19 NS NS NS 0.02 NS NS NS NS
Platelet
 Pre-challenge 429 534 450 483 447 415 44.8 NS NS NS NS NS NS NS NS
 6 h post-challenge 413 309 196 350 205 278 37.3 0.001 NS NS 0.0002 0.04 NS NS NS
 48 h post-challenge 445 345 350 338 322 345 29.9 NS NS NS 0.05 NS NS NS NS
 96 h post-challenge 449 446 386 520 427 507 61.3 0.06 NS NS NS NS NS NS NS
  1. a NCC non-challenged control pigs that were fed the basal diet and injected with sterile saline on d 7
  2. bPigs fed the basal diet without any additive (CC challenged control) or with AGP, YE, ENZ or ENZ + YE and injected with E. coli LPS on d 7
  3. c P-value for LPS + ENZ × LPS + YE interaction (CC, YE, ENZ and ENZ + YE)