Cellular reprogramming in farm animals: an overview of iPSC generation in the mammalian farm animal species

Table 1 Similarity (%) of OSKM protein sequences of different species to human and mouse (human/mouse)

Species	OCT4	SOX2	KLF4	c-MYC
Pig	93 / 86 [NP_001106531]	99 / 97 [NP_001116669]	96 / 92 [NP_001026952]	93 / 91 [NP_001005154]
Horse	94^a / 86^a [XP_001490158]	98^a / 96^a [ACJ12602]	94^a / 91^a [XP_005605741]	92^a / 91^a [XP_001498041]
Rabbit	90 / 85 [NP_001093427]	98^a / 99^a [AJC97786]	96^a / 92^a [AJC97787]	94^a / 92^a [XP_008254124]
Sheep	91^a / 84^a [XP_004019017]	100^a / 98^a [CAA65725]	96 / 93 [NP_001157691]	93 / 92 [NP_001009426]
Cattle	91 / 84 [NP_777005]	100 / 98 [NP_001098933]	96 / 93 [NP_001098855]	92 / 91 [NP_001039539]
Goat	91 / 84 [NP_001272498]	97 / 96 [NP_001272601]	96^a / 92^a [XP_005684447]	92^a / 92^a [XP_005689000]
Human	100 / 86 [NP_002692]	100 / 98 [NP_003097]	100 / 92 [NP_004226]	90 / 100 [NP_002458]
Mouse	86 / 100 [NP_038661]	98 / 100 [NP_035573]	92 / 100 [NP_034767]	100 / 90 [NP_034979]

ISSN: 2049-1891