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Table 4 Effect of clays on goblet cell number and size in ileum and colon of pigs experimentally infected with a pathogenic E. coli 1

From: Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs

 

Treatment2

 

P-value

 

Sham

E. coli

 

Main effect3

CON vs. SM4

Item

CON

SMA

SMB

ZEO

CON

SMA

SMB

ZEO

SEM

E. coli

Diet

E x D

Sham

E. coli

Ileum

              

Number5

25.54

23.58

23.67

25.62

27.42

25.00

32.42

26.87

3.08

< 0.01

0.16

0.06

0.49

0.71

Size6,7, μm2

29.47b

29.58b

31.88a,b

30.72b

31.00a,b

35.96a

30.65b

31.89a,b

0.764

0.01

0.18

0.01

0.32

0.15

Colon

              

Number

28.21

24.75

27.54

25.83

27.71

28.85

26.67

24.18

12.71

0.84

0.43

0.39

0.29

0.60

Size, μm2

26.26

27.33

27.60

30.37

25.56

28.31

25.82

27.69

0.801

0.20

0.04

0.41

0.09

0.21

  1. a-b Means with different superscripts in the same row differ.
  2. 1n = 8 pigs/treatment.
  3. 2Sham = unchallenged; E. coli = E. coli challenged; CON = control diet; SMA = 0.3% smectite A; SMB = 0.3% smectite B; ZEO = 0.3% zeolite.
  4. 3E. coli = E. coli challenge effect; Diet = diet effect; E x D = interaction between E. coli and diet effects.
  5. 4Contrast between CON and all clay treatments within challenge treatments.
  6. 5Goblet cell number; total number of goblet cells per villus, average of 3 villi.
  7. 6Goblet cell size, cross-sectional area.
  8. 7Con vs. SMA (Tukey adjustment) P = 0.07.