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Table 3 Differentially expressed genes in hypothalamus of WRR and XH chickens

From: Identification and characterization of genes that control fat deposition in chickens

Gene symbol

Gene title

P value

Fold-change

Chromosomes alignment

Lipid metabolic process

P20K

quiescence-specific protein

0,0109

-2,402

chr17:881078-883996

Porphyrin biosynthetic process

FECH

ferrochelatase (protoporphyria)

0,009

-2,155

chrZ:267090-278253

Nitrogen compound metabolic process

RCJMB04_35g11

vanin 1

0,0406

-2,312

chr3:58745711-58758866

Transport

PMP2

peripheral myelin protein 2

0,031

3,405

chr2:126148069-126152515

Ion transport

SLC22A2

solute carrier family 22 (organic cation transporter), member 2

0,004

-2,123

chr3:47342914-47355320

GLRA1

glycine receptor, alpha 1 (startle disease/hyperekplexia)

0,035

-2,146

chr13:12903161-12940509

sodium ion transport

SLC13A5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

0,003

-2,046

chr19:9754843-9769124

Copper ion transport

SLC31A1

solute carrier family 31 (copper transporters), member 1

0,017

7,335

chr17:1874758-1884555

Striated muscle contraction

MYBPC2

myosin binding protein C, fast type

0,034

-3,717

un

Response to stress

HSP70

heat shock protein 70

0,001

-2,093

chr5:55409752-55412248

HSP25

heat shock protein 25

0,006

-2,759

chr27:4486260-4487251

Signal transduction

LOC419724

similar to KIAA0712 protein

0,009

-2,393

chr24:1172171-1264246

cyclic nucleotide catabolic process

N4BP2L1

NEDD4 binding protein 2-like 1

0,006

3,732

chr1:178835487-178837064

Negative regulation of endothelial cell proliferation

TNFSF15

tumor necrosis factor (ligand) superfamily, member 15

0,027

2,553

chr17:2943951-2959613

Regulation of transcription, DNA-dependent

CREB3L2

cAMP responsive element binding protein 3-like 2

0,001

-2,197

chr1:59488049-59500378

MLL3

myeloid/lymphoid or mixed-lineage leukemia 3

0,008

-4,110

chr2:6484781-6486027

Protein complex assembly

ATPAF1

ATP synthase mitochondrial F1 complex assembly factor 1

0,003

-3,241

chr8:22570693-22574048

Protein amino acid phosphorylation

PRKD3

protein kinase D3

0,0005

-2,745

chr3:34793675-34819927

SGK1

serum/glucocorticoid regulated kinase 1

0,004

2,419

chr3:58130872-58134430

RIPK2

receptor-interacting serine-threonine kinase 2

0,013

2,532

chr2:129010265-129029220

Proteolysis

FOLH1

folate hydrolase (prostate-specific membrane antigen) 1

0,005

-2,344

chr1:191872775-191933212

C1R

complement component 1, r subcomponent

0,011

-2,014

chr1:80553474-80558910

ITGBL1

integrin, beta-like 1 (with EGF-like repeat domains)

0,024

2,43

chr1:147579457-147711379

VPS13B

vacuolar protein sorting 13 homolog B (yeast)

0,041

-2,155

chr2:133389475-133390863

  1. Positive values simply mean that the genes were up-regulated when WRR chickens are compared with XH chickens.
  2. Similarly, negative values mean down-regulation when comparison between WRR and XH chickens is made, Data were significantly different [P > 0, 05 (fold change ≥ 2)].