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Table 3 Differentially expressed genes in hypothalamus of WRR and XH chickens

From: Identification and characterization of genes that control fat deposition in chickens

Gene symbol Gene title P value Fold-change Chromosomes alignment
Lipid metabolic process
P20K quiescence-specific protein 0,0109 -2,402 chr17:881078-883996
Porphyrin biosynthetic process
FECH ferrochelatase (protoporphyria) 0,009 -2,155 chrZ:267090-278253
Nitrogen compound metabolic process
RCJMB04_35g11 vanin 1 0,0406 -2,312 chr3:58745711-58758866
Transport
PMP2 peripheral myelin protein 2 0,031 3,405 chr2:126148069-126152515
Ion transport
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 0,004 -2,123 chr3:47342914-47355320
GLRA1 glycine receptor, alpha 1 (startle disease/hyperekplexia) 0,035 -2,146 chr13:12903161-12940509
sodium ion transport
SLC13A5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 0,003 -2,046 chr19:9754843-9769124
Copper ion transport
SLC31A1 solute carrier family 31 (copper transporters), member 1 0,017 7,335 chr17:1874758-1884555
Striated muscle contraction
MYBPC2 myosin binding protein C, fast type 0,034 -3,717 un
Response to stress
HSP70 heat shock protein 70 0,001 -2,093 chr5:55409752-55412248
HSP25 heat shock protein 25 0,006 -2,759 chr27:4486260-4487251
Signal transduction
LOC419724 similar to KIAA0712 protein 0,009 -2,393 chr24:1172171-1264246
cyclic nucleotide catabolic process
N4BP2L1 NEDD4 binding protein 2-like 1 0,006 3,732 chr1:178835487-178837064
Negative regulation of endothelial cell proliferation
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15 0,027 2,553 chr17:2943951-2959613
Regulation of transcription, DNA-dependent
CREB3L2 cAMP responsive element binding protein 3-like 2 0,001 -2,197 chr1:59488049-59500378
MLL3 myeloid/lymphoid or mixed-lineage leukemia 3 0,008 -4,110 chr2:6484781-6486027
Protein complex assembly
ATPAF1 ATP synthase mitochondrial F1 complex assembly factor 1 0,003 -3,241 chr8:22570693-22574048
Protein amino acid phosphorylation
PRKD3 protein kinase D3 0,0005 -2,745 chr3:34793675-34819927
SGK1 serum/glucocorticoid regulated kinase 1 0,004 2,419 chr3:58130872-58134430
RIPK2 receptor-interacting serine-threonine kinase 2 0,013 2,532 chr2:129010265-129029220
Proteolysis
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1 0,005 -2,344 chr1:191872775-191933212
C1R complement component 1, r subcomponent 0,011 -2,014 chr1:80553474-80558910
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 0,024 2,43 chr1:147579457-147711379
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0,041 -2,155 chr2:133389475-133390863
  1. Positive values simply mean that the genes were up-regulated when WRR chickens are compared with XH chickens.
  2. Similarly, negative values mean down-regulation when comparison between WRR and XH chickens is made, Data were significantly different [P > 0, 05 (fold change ≥ 2)].